NS 21 - cerebellum and basal ganglia

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cerebellum and basal ganglia
Erica Lai
Flashcards by Erica Lai, updated more than 1 year ago
Erica Lai
Created by Erica Lai over 5 years ago
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Resource summary

Question Answer
which fossa is the cerebellum located in posterior cranial fossa
what is the sheet of dura mater that covers the cerebellum and separates it from the cerebrum called? tentorium cerebelli
what is the falx cerebri? it is a reflection of dura mater that divides the cerebral hemispheres
what structure divides the cerebellum into 2 lobes? the vermis
at which points does the cerebellum join the brainstem? superior cerebellar peduncle - midbrain middle cerebellar peduncle - pons inferior cerebellar peduncle - medulla
what are the 3 functional lobes of the cerebellum? cerebrocerebellum spinocerebellum vestibulocerebellum
cerebrocerebellum a.k.a. neocerebellum formed by lateral hemispheres plans + coordinates movements dentate nucleus is here
spinocerebellum a.k.a paleocerebellum formed by the vermis (midline) concerned with muscle tone and posture nuclei globose and emboliform are here
vestibulocerebellum a.k.a archicerebellum formed by flocculonodular lobe concerned with balance fastigial nucleus is found here
why are problems of the cerebellum ipsilateral? there is a double decussation
midline lesions affect which functional lobe(s) of the cerebellum? what are the consequences? vestibulocerebellum and spinocerebellum affected therefore you get nystagmus, loss of balance, disturbed + unsteady gait
lateral lesions affect which function lobe(s) of the cerebellum? what are the consequences? cerebrocerebellum affected therefore you get incoordination/intention tremor, unsteady gait (no sensory deficit and no muscular weakness)
bilateral dysfunction of the cerebellum presents with dysarthria (unclear articulation of speech) cerebellar ataxia (incoordination of both arms, wide-based unsteady gait)
what is the significance of the cerebellar tonsil position within the skull? they lie just above foramen magnum and so if a lumbar puncture is done to a patient with increased ICP they can herniate out, compressing the medulla --> disrupting normal HR, BP, breathing --> death
state the names of the 6 basal ganglia nulcei nucleus accumbens caudate nucleus putamen globus pallidus subthalamic nucleus substantia nigra
what makes up the corpus striatum? caudate nucleus + putamen + globus pallidus
what makes up the lentiform/lenticular nucleus? putamen + globus pallidus
what are the 2 parts of the substantia nigra and which part produces dopamine? pars compacta - dopamine pars reticulata
what are the 2 most important pathways in the basal ganglia and what are their functions? direct pathway allows purposeful movements indirect pathway prevents unwanted movements
inputs to direct/indirect pathways from cortex mainly thalamus substantia nigra (dopamine)
outputs from the striatum go to globus pallidus (internal segment) and pars reticulata of substantia nigra cortex (primary and supplementary motor regions) and UMNs (via the thalamus)
pathophysiology of Huntington's disease? neuronal loss in the striatum and cortex (frontal and parietal lobes)
what is chorea? brief sudden purposeless jerks
age of onset of Huntington's between 20-50 years
what is hemiballismus a rare movement disorder (a type of chorea) that results in flailing, ballistic, and undesired movement of limbs
hemiballismus is caused by lesion in contralateral subtalamic nucleus (can be due to MS)
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