1636757
Description
Flashcards by Justin Veazey, updated more than 1 year ago
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Created by Justin Veazey
over 9 years ago
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| Question | Answer |
| Antifungal agent | A drug that selective eliminates fungal pathogens |
| Antifungal relation to Antibacterial? | There are far less antifungal agents than antibacterial agents |
| Major/examples antifungal agents | Polyene macrolides Imidazoles Flucytosine Griseofulvin Iodides |
| Polyene macrolides; Drug names | Amphotericin B Nystatin Pimaricin (natamycin) |
| Polyene macrolides; Mode of Action | Bing Sterol-components in phospholipid sterol membranes. [Disrupts membranes] |
| What's unique about Polyene macrolides at a pH between 6-7.3 | Fungicidal>fungistatic |
| When do you use Amphotericin B? | Principally; Systemic mycotic infections |
| Tx?; Nystatin [Polyene macrolide] | Tx/Nystatin: Mucocutaneous (skin, oropharynx, vagina) or Intestinal Candidiasis |
| Tx:Pimaricin? [Polyene macrolides] | Pimaricin: Therapeutic management of mycotic keratitis |
| Imidazoles-uses | Anti-bacterial, Anti-fungal, Anti-protozoal, Anti-helmintic activity |
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