Antianginal drugs

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DRUGS Flashcards on Antianginal drugs, created by lauren.boone on 06/10/2013.
lauren.boone
Flashcards by lauren.boone, updated more than 1 year ago
lauren.boone
Created by lauren.boone over 10 years ago
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Question Answer
ORGANIC NITRATES (Glycerol Trinitrate and Isosorbide mononitrate) Powerful vasodilators particularly acting on veins (reducing cardiac preload) as well as cardiac collateral vessels. -GTN is short acting (first pass) - Isosorbide is long acting (second pass)
POTASSIUM CHANNEL ACTIVATORS Nicorandil combination of K(ATP) channel activation (reducing heart muscle activity) and nitrovasodilation actions.
BETE BLOCKERS Reduce HR and therefor cardiac output Also have an antidysrhythmic action.
VERAPAMIL CALCIUM ANTAGONIST antidysrhythmic action (slows ventricular rate in rapid atrial fibrillation to prevent recurrence of supraventricular tachycardia (SVT) binds to intracellular surface
DILTIAZEM CALCIUM CHANNEL ANTAGONIST vasodilators (mainly reducing afterload) and impair myocardial contractility and AV node conduction Treats angina
DIHYDROPIRINES (amlodipine and nifedipine) CALCIUM CHANNEL ANTAGONIST vasodilators (mainly reducing afterload) and impair myocardial contractility and AV node conduction Treat hypertension (and angina)
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