Created by lauren.boone
over 10 years ago
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Question | Answer |
ORGANIC NITRATES (Glycerol Trinitrate and Isosorbide mononitrate) | Powerful vasodilators particularly acting on veins (reducing cardiac preload) as well as cardiac collateral vessels. -GTN is short acting (first pass) - Isosorbide is long acting (second pass) |
POTASSIUM CHANNEL ACTIVATORS Nicorandil | combination of K(ATP) channel activation (reducing heart muscle activity) and nitrovasodilation actions. |
BETE BLOCKERS | Reduce HR and therefor cardiac output Also have an antidysrhythmic action. |
VERAPAMIL | CALCIUM ANTAGONIST antidysrhythmic action (slows ventricular rate in rapid atrial fibrillation to prevent recurrence of supraventricular tachycardia (SVT) binds to intracellular surface |
DILTIAZEM | CALCIUM CHANNEL ANTAGONIST vasodilators (mainly reducing afterload) and impair myocardial contractility and AV node conduction Treats angina |
DIHYDROPIRINES (amlodipine and nifedipine) | CALCIUM CHANNEL ANTAGONIST vasodilators (mainly reducing afterload) and impair myocardial contractility and AV node conduction Treat hypertension (and angina) |
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