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Description
Flashcards by Kara Robbins, updated more than 1 year ago
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Created by Kara Robbins
almost 9 years ago
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| Question | Answer |
| What is the Citric Acid Cycle (CAC) also known as, and where does it occur? | The Citric Acid Cycle is also known as the Krebs Cycle, and occurs in the inner mitochondrial matrix. |
| What steps link glycolysis to the Citric Acid Cycle? What molecule enters and what is produced? | Pyruvate Dehydrogenase Complex (PDH) connects glycolysis and CAC. Pyruvate enters and 1 Acetyl CoA and 1 NADH is produced. |
| How many NADH, FADH2, and GTP are produced in the CAC per Acetyl CoA (per glucose molecule)? | 6 NADH 2 FADH2 2 GTP |
| How many ATPs can be produced at the ETC from each NADH and FADH2? How is this different from the NADH produced in glycolysis? | NADH can produce 3 ATP at the ETC FADH2 can produce 2 ATP at the ETC. In glycolysis, NADH & FADH2 produce 2 ATP only. |
| How many steps are there in the CAC, and how to the first and last steps link? | There are 8 steps, and the first step (Acetyl CoA) requires the last step (oxaloacatate) to be able to start the Cycle. |
| What happens in step 1? | Acetyl CoA enters the cycle, is catalyzed by citrate synthase and becomes citrate. |
| What happens in step 2? | Citrate becomes isocitrate. |
| What happens in step 3? | Isocitrate becomes alpha-ketaglutarate (1 NADH is produced), catalyzed by isocitrate dehydrogenase. Co2 is produced as waste. |
| What happens in step 4? | Alpha-ketaglutarate becomes succinyl-CoA. 1 NADH is produced. Co2 is produced as waste. |
| What happens in step 5? | Succinyl-CoA becomes succinate. 1 GTP is produced. |
| What happens in step 6? | Succinate becomes fumarate. 1 FADH2 is produced. |
| What happens in step 7? | Fumarate becomes malate. |
| What happens in step 8? | Malate becomes oxaloacetate, and 1 NADH is produced. Oxaloacetate then goes onto Acetyl CoA to continue the cycle. |
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