536687
Description
Flashcards by gina_evans0312, updated more than 1 year ago
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Created by gina_evans0312
almost 12 years ago
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| Question | Answer |
| Basis of Catcholamines | Tyrosine- made into a catechol ring & a modifiable amide base |
| Noradrenaline- Location | Central nervous system and sympathetic nervous system |
| Noradrenaline- Action | Generally inhibitory |
| Noradrenaline- Method of work | Hyperpolarisation |
| Noradrenaline- Excess | Mania |
| Noradrenaline- Deficiency | Depression |
| Dopamine- Location | A central nervous system |
| Dopamine- Action | Primarily inhibitory |
| Dopamine- Excess | Schitzophrenia/Psychosis |
| Dopamine- Deficiency | Parkinsons |
| Adrenaline- Production | Chromaffin cells in adrenal medulla |
| Adrenaline- Location | CNS |
| Adrenaline- Action | Fight or flight response |
| Hypertension- Catcheolamines | Increased CA's increase vascular tone and blood pressure |
| CA Production- Tyrosine | Basis of all CA's |
| CA Production- DOPA | Created from tyrosine using Tyrosine Hydroxylase |
| CA Production- Dopamine | Produced from DOPA using DOPA decarboxylase |
| CA Production- Noradrenaline | Created from Dopamine using Dopamine-Beta-Hydroxylase (found in vesicles, where it's stored) |
| Adrenaline | Created from Noradrenaline using Phenylethanolamine & S-Adenosyl Methionine, and is stored in vesicles |
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