101552
Description
Mind Map by Caroline Oxford, updated more than 1 year ago
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Created by Caroline Oxford
almost 11 years ago
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Blood Physiology
- Blood Values
- Haematocrit (packed RBC)= 45%
- Volume About 5l
- Plasma K+ 4.5 mmol/l-1
- Plasma Na+ 140 mmol/l-1
- Random Glucose 5 mmol/l-1 Fasting 4.4-6.1
- Platelet count 300,000/mm3
- pH 7.35-7-45
- Plasma volume 40ml kg-1 body weight
- Haemoglobin count 12-14 W, 14-16g/dl-1 in men
- RBC count 4-6x10 to the 12L-1
- RBC count 4-6x10 to the 12L-1
- Haemoglobin count 12-14 W, 14-16g/dl-1 in men
- Plasma volume 40ml kg-1 body weight
- pH 7.35-7-45
- Platelet count 300,000/mm3
- Random Glucose 5 mmol/l-1 Fasting 4.4-6.1
- Plasma Na+ 140 mmol/l-1
- Plasma K+ 4.5 mmol/l-1
- Volume About 5l
- Haematocrit (packed RBC)= 45%
- Plasma 55%
- Albumin
- A protein made in liver
- highest concentration, contributes to colloid osmotic pressure
- A protein made in liver
- Globulins
- specific transport proteins
- eg. Transferrin for iron
- eg. Transferrin for iron
- Clotting factors
- Inactive precursors of certain hormones
- eg. Angiotensinogen
- eg. Angiotensinogen
- Immunoglobulins, act as circulating antibodies
- specific transport proteins
- Fibrinogen
- converted to Fibrin during clotting
- converted to Fibrin during clotting
- Serum=Plasma without Fibrinogen (Platelets)
- Albumin
- Erythrocytes
- Develop in liver, spleen + lymph nodes before birth
- Develop in the marrow of long bones, then ribs, pelvis etc as we get older
- formed from Erythroid cell (committed stem cell)
- 120 day life span
- 120 day life span
- Erythropoiesis
- controled by Kidneys- Produces Erythroprotein
- Reads O2 levels, not haemoglobin level
- High altitudes increases Erythropoiesis
- High altitudes increases Erythropoiesis
- Reads O2 levels, not haemoglobin level
- Needs VitB12 & Folic acid
- From Diet
- Parietal cells in stomach, secrete intrinsic factor which binds to B12
- Lack of Intrinsic factor, results in less VitB12. Pt often jaundice from Bilirubin (from breakdown of RBC)
- Lack of Intrinsic factor, results in less VitB12. Pt often jaundice from Bilirubin (from breakdown of RBC)
- Needs Iron for Haemoglobin
- Parietal cells in stomach, secrete intrinsic factor which binds to B12
- From Diet
- controled by Kidneys- Produces Erythroprotein
- Blood Groups
- 0 Group
- No Antigens on cell
- Anti-A & Anti-B in plasma
- Universal Donor
- Must receive O
- Must receive O
- Universal Donor
- Anti-A & Anti-B in plasma
- No Antigens on cell
- A Group
- A Antigens
- Anti-B
- Must recieve A
- All 3 can recieve O
- All 3 can recieve O
- Must recieve A
- Anti-B
- A Antigens
- B Group
- B Antigens
- Anti-A
- Must recieve B
- Must recieve B
- Anti-A
- B Antigens
- AB Group
- A&B Antigens
- No Antibodies
- Universal recipient
- Universal recipient
- No Antibodies
- A&B Antigens
- All IgM antibodies
- 0 Group
- Develop in liver, spleen + lymph nodes before birth
- WBC + Platelets
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