13420785
Description
Mind Map by Deleted user, updated more than 1 year ago
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Created by Olivia McRitchie
about 6 years ago
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Copied by Olivia McRitchie
about 6 years ago
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Bipolar Disorder
- Characteristics
- Depression looks
like typical major
depression
- Mania looks like inflated
self-esteem, decreased
need for sleep, increased
talkativeness, racing
thoughts, distractability,
increased goal-directed
activities, and excessive
involvement in
dangerous but
pleasureable activity.
- Must be
present for
at least 1
wk.
- Hypomania is
same symptoms,
less severe.
- Excess of excitatory
neurotransmitter or
deficiency of
inhibitory
neurotransmitters
- Excess of excitatory
neurotransmitter or
deficiency of
inhibitory
neurotransmitters
- Must be
present for
at least 1
wk.
- Depression looks
like typical major
depression
- Medications
- Sometimes
called mood
stabilizers.
- Lithium,
antiseizure drugs,
and atypical
antipsychotics.
- Lithium (Eskalith)
- Effective for purely
manic or purely
depressive
episodes.
- Narrow therapeutic
range; monitored by
serum levels every
4-5 days, then 5 days
after every dose
change.
- Must remain
within 0.6-1.5
mEq/L
- Close monitoring
encourages
compliance and
helps prevent
toxicity.
- Close monitoring
encourages
compliance and
helps prevent
toxicity.
- Acts like sodium in
body, so when sodium
is greatly reduced,
chance of lithium
toxicity increases.
- Necessary to monitor
sodium levels
- Overdose treated
w/hemodialysis and
supportive care.
- Baseline for renal,
electrolyte, cardiac, and
thyroid status is
indicated.
- Polypharmacy is
not unusual for this
drug.
- Lithium +TCA or bupropion
(atypical antidepressant):
Good for depressive
episodes.
- Lithium +benzo= Good for manic
episodes.
- If serious agitation, delusion, or
hallucination happens: Lithium +
antipsychotic.
- If serious agitation, delusion, or
hallucination happens: Lithium +
antipsychotic.
- Lithium +benzo= Good for manic
episodes.
- Lithium +TCA or bupropion
(atypical antidepressant):
Good for depressive
episodes.
- Polypharmacy is
not unusual for this
drug.
- Baseline for renal,
electrolyte, cardiac, and
thyroid status is
indicated.
- Necessary to monitor
sodium levels
- Must remain
within 0.6-1.5
mEq/L
- Narrow therapeutic
range; monitored by
serum levels every
4-5 days, then 5 days
after every dose
change.
- Effective for purely
manic or purely
depressive
episodes.
- Valproic acid
(Depakene/Depakote),
carbamazepine (Tegretol), and
lamotrigine (Lamictal)
- Antiseizure drugs that can be
used for rapidly cycling and
mixed states of bipolar.
- Antiseizure drugs that can be
used for rapidly cycling and
mixed states of bipolar.
- Gabapentin (Neurontin),
oxcarbazepine (Trileptal),
topiramate (Topamax,
and zonisamide
(Zonegran)
- Aripiprazole (Abilify), asenapine
(Saphris), olanzapine (Zyprexia),
qurtiapine (Seroquel), risperidone
(Risperdal), and ziprasidone
(Geodon)
- Atypical antipsychotics that treat
extreme mania and bipolar disorder.
- Black box warning: don't use for
patients w/dementia-related
psychosis
- Black box warning: don't use for
patients w/dementia-related
psychosis
- Atypical antipsychotics that treat
extreme mania and bipolar disorder.
- Sometimes
called mood
stabilizers.
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