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Epithelial tissue

Morgan Morgan

GnRH Mechanism

Description

GnRH Mechanism experiment

Mind Map by Alexandra McCabe, updated more than 1 year ago

	Created by Alexandra McCabe about 10 years ago

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Resource summary

GnRH Mechanism

Desensitization
1. Slow Rise rate looks like continous stimulation
Effect on FSH release
1. Stimulatary patterns did not change the release of LH/FSH
  1. Due to desensitization to GnRH pulses
2. Ratio of FSH:GnRH due to
  1. Differential Clearance
  2. Ovarian Feedback
  3. Differential Synthesis in intact tissue
  4. Other hormones that cause FSH secretion
Steroid Feedback Mechanism
1. Castrated
  1. Males
    1. Effects Testosterone that decreases frequency and amplitude
  2. Females
    1. Increases GnRH receptors but blocked if estrogen or other steroids are given
Stimulatory Signals
1. Pulse Amplitude
2. Interval
3. Duration
4. Rise Rate
Graph Shows
1. For effective reponse
  1. Pulse
    1. Wide Spread
    2. Short
2. A large about of LH released when GnRH added

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