Glucose Oxidation

Glycolysis
1. does not involve oxygen
2. little energy is produced - only 2 ATP per glucose
3. end products in presence of oxygen = pyruvate and NADH
4. NADH re-oxidation is achieved by the enzyme lactate dehydrogenase which converts pyruvate to lactate
  1. lactate is released into the blood and recycled by the liver
Citric Acid Cycle
1. most of the cells energy is made in the mitochondria
2. occurs in matrix of mitchondria
3. pyruvate is fed into the citric acid cycle by acetyl-coenzyme A
  1. Acetlyl CoA = acyl group carrier
Oxidative decarboxylation of pyruvate
1. two molecules of carbon dioxide are formed
2. two electrons are transferred to NAD+
  1. 3 NADH are produced
  2. 1 FADH produced
3. acetyl group is transferred to CoA
4. large free energy decrease
Electron transport chain
1. delta G for the transfer of electrons from NADH to oxygen to form water is -220kJ mol
2. determination of redox potentials
  1. a more negative redox potential value signifies more readiness to donate electrons
  2. Eo values
    1. all coponents at 1M
    2. hydrogen gas at 1 atmospheric pressure
    3. pH = 7
    4. relationship between Gibbs free energy and redox potential difference
      1. delta G = -nFdeltaEo

Resource summary

	Created by kathrynmoar over 10 years ago