The body's Defense against Antigens

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MacKenna Westerf
Mind Map by MacKenna Westerf, updated more than 1 year ago
MacKenna Westerf
Created by MacKenna Westerf over 8 years ago
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Resource summary

The body's Defense against Antigens
  1. Non- specific Defenses
    1. Chemical barriers
      1. Fatty acids, proteins, bodily secretions, and other substances with natural attributes that help defend the body against disease or infection. Such substances may have a low pH, or serve to breakdown or destabilize bacterial cells.
        1. Stomach Acid (lactobacillus)
          1. The stomach uses gastric acid with a pH2 to kill the microbes, but some bacteria survive by being inside food as it goes through, others by producing a cloud of ammonia.
          2. Ear Wax
            1. Ear wax is slightly acidic and will kill off any bacteria that cannot stand the acidity that enters through the ear
            2. Salty tears
              1. Kill the microbes that are not able to live with the salt
              2. Mucus
                1. sticky mucus in the lungs traps microbes, and then cilia sweep it out of the lungs
                2. Sweat
                  1. Posesses antibacterial properties which have hight levels ofacidity
                3. Phagocytes
                  1. Phagocytes are the white blood cells that protect the body by ingesting harmful foreign particles, bacteria, and dead or dying cells.
                    1. When there is an infection, phagocytes move to the bacteria by sensing chemicals. When the bacteria touches a phagocyte, they bind to its receptor and is eaten. The phagocyte then moves parts of the killed bacteria back to its surface. These parts are then shown to other cells of the immune system. They then move to the body's lymph node and show the bacterial parts to white blood cells called lymphocytes. This action is important in getting immunity.
                  2. Mechanical Barriers
                    1. A mechanical barrier in the immune system is a primary line of defense, which physically impedes the entry of foreign particles that may harm the body.
                      1. Ear drum
                        1. Stops water and unwanted microbes from entering the body
                        2. Nose hairs
                          1. Trap microorganisms and prevents them from entering the body
                          2. Ciliated lining in nose and lungs
                            1. Traps mucuse which traps the microorganisms in the mucus
                            2. Skin
                              1. Prevents any microorganisms to get into your body. Acts as a protective shield.
                          3. Specific Defenses
                            1. Antibody
                              1. Bacteria
                                1. Bacteria are tiny single-cell microorganisms, usually a few micrometers in length that normally exist together in millions.
                                2. Virus
                                  1. A virus is a microscopic organism consisting of genetic material (RNA or DNA) surrounded by a protein, fat, or glycoprotein coat.
                                  2. Antibodies are large Y-shaped proteins. They are recruited by the immune system to identify and neutralize foreign objects like bacteria and viruses.
                                  3. Memory Cells
                                    1. T Cells
                                      1. Killer
                                        1. Killer T-cells hunt down and destroy cells that are infected with germs or that have become cancerous.
                                        2. Helper
                                          1. They are required for almost all adaptive immune responses, which activate killer t-cells, Macrophage, and B cells to secrete antibodies
                                        3. B Cells
                                          1. These lymphocytes, are designed to provide immunity in the body by developing antibodies when they are exposed to antigens, that invoke an immune response. B cells are produced in the bone marrow, which provides a steady supply of them to the body. They later mature into plasma B cells.
                                            1. Plasma B cell
                                              1. Once released into the blood, these antibody molecules bind to the target antigen and initiate its neutralization or destruction.
                                          2. Any small, long-lived lymphocyte that has previously encountered a given antigen and that on reexposure to the same antigen rapidly initiates the immune response (memory T cell) or proliferates and produces large amounts of specific antibody (memory B cell) the agent of lasting immunity.
                                          3. Vaccinations
                                            1. Getting a vaccine is something that will help your body to protect itself from an infection in the future. Vaccines help develop immunity by imitating an infection, but this infection does not cause illness. It does, however, cause the immune system to develop the same response as it does to a real infection so the body can recognize and fight the vaccine in the future.
                                              1. Dead Cell
                                                1. These vaccines are similar to DNA vaccines in that they introduce DNA from a harmful pathogen into the body, triggering the immune system to produce antigens and train itself to identify and combat the disease.
                                                2. Similar Cells
                                                  1. For these types of vaccines, a weaker, asymptotic form of the virus or bacteria is introduced into the body. Because it is weakened, the pathogen will not spread and cause sickness, but the immune system will still learn to recognize its antigens and know to fight in the future.
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