455441
Description
Mind Map by Shaima Amanda, updated more than 1 year ago
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Created by Shaima Amanda
over 10 years ago
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Blood pressure
- Major regulator: Renin
- Juxtaglomerular cells
- Cleaves Angiotensinogen to AT-1
- AT-1 to AT-2
- Stimulates adrenal gland to secrete aldosterone
- Increases blood volume
- -ve feedback by Myocardial natriuretic peptide
- -ve feedback by Myocardial natriuretic peptide
- Increases blood volume
- Increases sodium resorption
- Vasoconstriction
- Stimulates adrenal gland to secrete aldosterone
- AT-1 to AT-2
- Juxtaglomerular cells
- Benign Hypertension
- Malignant Hypertension
- Hyperplastic arteriosclerosis
- Decreased sodium excretion
- Increased
blood volume
and blood
pressure
- Increased
blood volume
and blood
pressure
- Genetic factors/
Environmental factors
- Atherosclerosis
- Atheroma
- Cholesterol,
cholesterol
esters, necrotic
debris and fibrotic
caps
- Cholesterol,
cholesterol
esters, necrotic
debris and fibrotic
caps
- Thrombosis
- Risk Factors
- Modifiable
- Hyperlipidemia/ hypercholesterolemia
- Good cholesterol
- HDL. HDL
mobilzes the
cholesterols
from plaques
to the liver
- Exercise and ethanol increases HDL
- Smoking and obesity decreases HDL
- Exercise and ethanol increases HDL
- HDL. HDL
mobilzes the
cholesterols
from plaques
to the liver
- Bad cholesterol
- LDL. LDL distributes
the cholesterol in the
peripheral tissues
- Statins lower the circulating cholesterol
- Statins lower CRP levels
- CRP is synthesised by liver.
It is a biomarker which
predicts the risk of MI.
- CRP is synthesised by liver.
It is a biomarker which
predicts the risk of MI.
- Statins lower CRP levels
- Statins lower the circulating cholesterol
- LDL. LDL distributes
the cholesterol in the
peripheral tissues
- Good cholesterol
- Hypertension
- Ischemic heart disease
- Left ventricular hypertrophy
- Ischemic heart disease
- Smoking
- Diabetes mellitus
- Atherosclerosis
related GANGRENE
- Myocardial infarction
- Atherosclerosis
related GANGRENE
- Hyperlipidemia/ hypercholesterolemia
- Constitutional/
nonmodifiable
- Genetics
- Familial hypercholesterolemia
- Familial hypercholesterolemia
- Age
- 40-60 yrs
- 40-60 yrs
- Gender
- Males are more prone. Postmenopausal women are
also at more risk compared to premenopausal
- Males are more prone. Postmenopausal women are
also at more risk compared to premenopausal
- Genetics
- Modifiable
- Coronary Artery Disease
- Lipoprotein-a :
Apolipoprotein B100 and
Apolipoprotein-a
- Lipoprotein-a :
Apolipoprotein B100 and
Apolipoprotein-a
- Atherogenesis
- Endothelial injury
- Endothelial dysfunction
- Monocyte-macrophages
- Platelet adhesion
- Smooth muscle recruitment
- Lipid accumulation
- Fatty streaks
- Atherosclerotic plaques
- Smooth
muscle cells,
T-cells and
macrophages
- Intracellular and
extracellular lipid
accumulation
- ECM, collagen,
elastin,
proteoglycans
- LEADS TO THROMBOSIS
- EMBOLISM
- Plaque rupture
- Plaque erosion
- Plaque hemorrhage
- EMBOLISM
- Smooth
muscle cells,
T-cells and
macrophages
- Atherosclerotic plaques
- Endothelial injury
- Atheroma
- Hyperplastic arteriosclerosis
- Hyaline arteriosclerosis
- Nephrosclerosis
- Nephrosclerosis
- Malignant Hypertension
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