Yr9 Biology - Infectious Diseases (GCSE AQA B1.1.2)

T Mason
Mind Map by T Mason, updated more than 1 year ago
T Mason
Created by T Mason about 6 years ago
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GCSE Science (Biology) Mind Map on Yr9 Biology - Infectious Diseases (GCSE AQA B1.1.2), created by T Mason on 05/15/2014.

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Yr9 Biology - Infectious Diseases (GCSE AQA B1.1.2)
1 Microogranisms that cause infectious disease are called pathogens and they get inside our bodies through:
1.1 DROPLET INFECTION - cilia cells push up the pathogen with mucus. Cough, sneeze or talk contaminate droplets of mucus/breath. E.g. cold, flu, measles, chicken pox, TB
1.2 THROUGH CONTACT - skin has oil on it for sanitation
1.3 THROUGH BREAKS IN THE SKIN - our body forms a scab
1.4 THROUGH CONTAMINATED FOOD & DRINK - hydrochloric acid in stomach reacts to pathogen
1.5 PATHOGEN - microorganism that can infect our bodies
1.6 NATURAL BARRIER - what our body creates to fight infection
1.7 MICROORGANISM - small organism that can only be seen through a microscope
2 Bacteria and viruses may reproduce rapidly inside the body and may produce poisons (toxins) that makes us feel ill. Viruses damage the cells in which they reproduce
3 The immune system of the body produces specific antibodies to kill a particular pathogen. This leads to immunity from that pathogen. In some cases, dead or inactivated pathogens stimulate antibody production (called a vaccine). If a large proportion of the population is immune to a pathogen, the spread of the pathogen is reduced massively.
4 Semmelweis recognised the importance of hand-washing in the prevention of spreading some infectious diseases in May 1847. By insisting that doctors washed their hands before examining patients, he greatly reduced the number of deaths from infectious diseases in his hospital.
4.1 Handwashing removes/+kills pathogens on hands so that you do not transfer bacteria directly/indirectly
5 Some medicines, including painkillers, help to relieve the symptoms of infectious disease, but do not kill the pathogen
6 Antibiotics, incl. penicillin, are medicines that help to cure bacterial disease by killing infectious bacteria inside the body. Antibiotics cannot be used to kill viral pathogens, which live and reproduce inside cells. It is important that specific bacteria should be treated by specific antibiotics. The use of antibiotics has greatly reduced deaths from infectious diseases.
7 Strains of bacteria, incl. MRSA, have developed resistance to antibiotics as a result of natural selection. To prevent further resistance arising it is important to avoid over-use of antibiotics.
8 Mutations of pathogens produce new strains. Antibiotics and vaccinations may no longer be effective against a new resistant strain of the pathogen. New strain will spread rapidly because people are not immune to it and there is no effective treatment.
9 People can be immunised against a disease by introducing small quantities of dead or inactive forms of the pathogen into the body (vaccination). Vaccines stimulate the white blood cells to produce antibodies that destroy the pathogen, artificially creating primary immune response. This makes the person immune to future infections by the microorganism. The body can respond by rapidly making the correct antibody, in the same way as if the person had previously had the disease.
10 Immune System
10.1 The body has different ways of protecting itself against pathogens
10.2 White blood cells
10.2.1 produced in bone marrow
10.2.2 Two main types
10.2.2.1 phagocytes
10.2.2.1.1 sends out projections called pseudopodia (this surrounds pathogen, digests it and gets rid of it)
10.2.2.1.2 PHAGOCYTOSIS - when a pathogen enters the body, white blood find the bacteria using chemotaxis (detecting toxins bacteria releases) and sends out toxins to engulf the pathogen
10.2.2.1.2.1 STAGES: moves to site of injury --> detects pathogen using chemotaxis --> adheres to pathogen --> sends out pseudopodia --> engulfs pathogen --> digests pathogen --> destroys pathogen
10.2.2.2 lymphocytes
10.2.3 when pathogens are in body, WBCs squeeze through epithelials (blood vessel walls) to absorb pathogens, releasing enzymes and sending out messages to bring other WBCs to affected area
11 Antitoxins & Antibodies
11.1 Pathogens harms bodies by attacking cells by taking over them and preventing them from taking out functions and causing cell damage by breaking it open and killing it faster that the body can fight against it.
11.2 Bacteria releases toxins
11.3 Viruses cause cell damage
11.4 1. White blood cells secrete antitoxins and release them into blood stream. 2. Antitoxins neutralise toxins by binding to them
11.4.1 1895 - American started to produce antitoxins to treat dipitheria (a bacterial disease)
11.5 Antibodies are produced by white blood cells and destroy antigens on the outside of pathogens
11.5.1 1. Body recognises pathogens as foreign (due to differently shaped antigens from our body cells) and white blood cells come to affected area
11.5.2 2. WBC, specifically LYMPHOCYTES, release antibodies shaped specifically to bind to the antigens of the pathogen
11.5.3 Functions are: to clump together, destroy and label pathogens for destruction.
12 Memory cells
12.1 body remembers pathogens through white blood cells which become 'memory cells'
12.2 have a long longjevity
12.3 remember foreign cells so if infected again, white blood cell response is quicker
12.4 one particular memory cell remember one particular pathogen
13 MMR Vaccine
13.1 stops us from getting viral diseases: measles, mumps, and rubella. Contain weak form of each virus
13.2 Measles = highly contagious infectious disease characterized by a high fever, a rash and generally feeling unwell. 430 deaths from measles occur daily. Potentially fatal and childhood disease.
13.3 MMR = combined vaccine against measles, mumps and rubella. Introduced in the UK in 1988
13.4 People were worried about it because in 1998, a study published in The Lancet raised the possibility that the jab may be linked to autism and bowel disease
13.4.1 not tested so not certain
13.4.2 just observation, no scientific evidence
13.5 Issues with Wakefield's study
13.5.1 12 people - not enough tested
13.5.2 only included those infected (lack of a control)
13.5.3 Lawyers may choose cases - not random and introduces bias
13.5.4 Observations carried out by non-professionals (parents)
13.5.5 Wakefield paid and had obsession with autism (conflict of interest)
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