903226
Description
Mind Map by Zulhilmi Zainal, updated more than 1 year ago
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Created by Zulhilmi Zainal
almost 10 years ago
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Molar pregnancy/ hydatidiform mole
- an egg that is missing its nucleus is fertilized and
that may or may not contain fetal tissue
- complete moles
- single (90%) or two (10%) sperm combining with an egg which has lost
its DNA (the sperm then reduplicates forming a "complete" 46
chromosome set
- higher risk of developing into choriocarcinoma
- all the chorionic villi are vesicular, and no sign of embryonic or fetal development is present
- single (90%) or two (10%) sperm combining with an egg which has lost
its DNA (the sperm then reduplicates forming a "complete" 46
chromosome set
- partial mole
- an egg is fertilized by two sperm or by one sperm
which reduplicates itself yielding the genotypes of
69,XXY (triploid) or 92,XXXY (tetraploid)
- fetus is always malformed and is never viable
- an egg is fertilized by two sperm or by one sperm
which reduplicates itself yielding the genotypes of
69,XXY (triploid) or 92,XXXY (tetraploid)
- complete moles
- spontaneous abortion if untreated
- Clinical presentation
- painless vaginal bleeding in the
fourth to fifth month of
pregnancy
- uterus may be larger than expected, or the ovaries
may be enlarged
- hyperemesis
- very high levels of human chorionic
gonadotropin (hCG)
- "cluster of grapes" or "honeycombed uterus" or "snow-storm"
- increased trophoblast proliferation and enlarging of the chorionic villi
- sonogram & histopathological examination
- painless vaginal bleeding in the
fourth to fifth month of
pregnancy
- Treatment
- surgical curettage
- avoid the risks of choriocarcinoma
- avoid the risks of choriocarcinoma
- avoid pregnancy for at least 6 to 12 months
- surgical curettage
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