Parenterals Part 3 Notes

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Dosage I (Exam II) Note on Parenterals Part 3 Notes, created by hadi_dalati on 30/11/2013.
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Types of Plastics:Polyethylene (squeezable)Polypropylene (can be autoclaved)Polyvinyl Chloride (rigid)Di-ethylhexylphthalate (DHEP) is a plasticizer added to Polyvinyl Chloride plastics

Laminar Flow Hoods (LFH) must be Class 100 (less than 100particles of 0.5 micron size/cubic foot)

HEPA remove particles 0.3 microns and larger

Methods of sterilization:Autoclave:121 C20 min15 pounds of pressurenot for oily or moisture sensitive preparationsDry Heat Sterilization:160-170 C≥ 2 hoursNot for heat sensitive preparationsSterilization by filtration:14 to 0.025 micrometersGaseous Sterilization:Ethylene Oxide used with CO2 gas to avoid explosions4-16 hours neededNot for solutions

Glass:Type I: BorosilicateType II: treated Soda LimeType III: Soda Lime

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