Created by janiceyipp
almost 10 years ago
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Copied to Note by janiceyipp
almost 10 years ago
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Acetycholine AcH (PRE & PARA POST)
Norephephine NE (SYM POST)eprinephine
Pre-ganlionic axons Synapse @ 1st sym --> ^or v paravert ganglion continue to prevertebral Extend or terminate @ adrenal medulla
Adrenoceptors α (1,2) β (1,2,3) Blood Vessel Heart Constriction Dilation Thrombocytes ^ contractibility Bronchi Aggregation Kidney Dilation Adipocytes Vasoconstriction Renin release (X tubular Na reabsorb) Inhibit lipolysis Lipolysis (triglycerides--> 3 fatty acid + glycerol
Sympathomimetics direct on a &β indirectly on pre-syn terminal Agonist Antagonist X selective Adrenaline α selective β 2 B P + Bronchi Dil Vasopressor Anaphlatic shock treatment 1- nasal decongestant 2 hypotensive drugs Phenylephrine Ephedrine clonide methyldopa Salbutamol β1 Propanolol Atenolol
Cholinomimetics on recpetor Muscarinic Pilocarpine Amanita Muscaria 菇
mimic norepinephine and epinphrine
+reduced BP
a type of allergy, cause death
Dilate bronchial smooth muscle used as aerosol for Asthma if not selective, +heart side effect
Side effect: Bronchial constriction CardioVascular app: H. fail, Stage fright Hypertension Angina Cardiac arhythmias
Eye drop intraocular pressure - for glaucoma 青光眼
BP v 口水 淚水 汗+ adominal pain, nausea death due to H & lung failure
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Neurotransmitter
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