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Flashcards

Colon histology

Iain Sheriffs Histopathology Frcpath Inglês 13 flashcards

Flashcards do conjunto (13)

  1. 1Mucosa-Smooth without folds
    -No villi
    -Crypts of Lieberkuhn
    -0.5mm straight and extend from lumen to the muscularis mucosae
  2. 2Mucosa-Epithelial lining of columnar cells with abundance of globlet cells and small number of endocrine cells
  3. 3Epithelium-Turnover of the colonic surface epithelium takes 3 to 8 days
  4. 4Absorptive cells-Columnar cells
    -Basally located round nuclei
    -Short microvilli on surface
  5. 5Goblet cells-More in colon than small bowel
    -Most abundant in sigmoid and rectum
    -1 per 4 columnar cells
    -Nuclei compressed basally
    -Mucin stains with Alcian blue at pH2.5 and 1.0
  6. 6Endocrine cells-Colon has less than any other part of GIT
    -Located in proximal and distal colon
    -Most prominent in base of crypts
    -Clear or eosinophilic cytoplasm
  7. 7Paneth cells-Present scattered in caecum and prox A colon
    -Absent from rest of colon
  8. 8Lamina propria-Separates the crypts
    -Consist of loose, reticular connective tissue
  9. 9Lamina propria-Contains:
    Fibroblasts
    Capillaries
    Macrophages
    Plasma cells
    Lymphocytes
    Scattered mast cells
  10. 10Lamina propria-Solitary lymphoid follicles are present which can displace crypts and extend into the submucosa
    -Increase towards the rectum
    -Larger in children
  11. 11Submucosa-Contains collagen, reticulin fibres, elastic tissue, nerves, blood vessels, lympahtics, ganglion cells and variable amounts of fat
  12. 12Muscularis propria-Bands of smooth muscle separated by connective tissue (elastic and collagen)
    -Myenteric (Auerbach) plexus is found between both layers
  13. 13Serosa-Located outside of the longitudinal muscle
    -Contains blood vessels and lymphatics
    -Covered by peritoneum
    -Elastic lamina present below the peritoneal cells

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Frcpath Histopathology (Colon) FlashCards sobre Colon histology, criado por Iain Sheriffs em 12-02-2021.
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Iain Sheriffs
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