Flashcards
Schistosomes (trematodes)
Flashcards do conjunto (13)
- 1DistributionEndemic > 70 tropical and sub-tropical countries
200 million people infected - 600 million people at risk
In sub-Saharan Africa >200 000 deaths per year - 2The main species (major)S. mansoni (Africa)
S. haematobium (Africa and Middle East)
S. japonicum (S.E. Asia and China) - 3Life cycleHere it is!!
- 41. Humans excreteHumans faece ad urinate eggs (diagnosis stage)
- 52. MiracidiaEggs hatch to release miracidia
- 63. Miracidia penetrationMiracidia penetrate snail tissue and form sporocysts in successive generations.
- 74. The cercariaeCercariae are released by snail and are free-living (infectious)
- 85. Humans swim in freshwaterCercariae penetrate through skin and lose tail becoming schistosomulae
- 96. CirculationCirculates in blood before migrating to hepatic blood and mature into adults
- 107. The paired adult worms (dioecious and sexually dimorphic)They migrate to mesenteric venules of bowel/rectum (laying eggs that circulate to the liver and shed in stools) venus plexus of the bladder.
- 11Clinical featuresCercarial dermatitis
Parasite maturation (acute schistosomiasis)
Established infection
Late stage infections - 12DiagnosisEgg in stool or urine
Ultrasound
Bladder biopsy
Serological testing - 13Treatment (Praziquantel)- Effective against trematodes (and cestodes)
- Single dose
- Few side effects
- Few contra-indications
Informações
- Descrição
- BIOL 123: Immunisation FlashCards sobre Schistosomes (trematodes), criado por Jumael Zafar em 05-02-2019.
- Criado por
- Jumael Zafar · fev 2019
- Atualizado
- 6 fev 2019
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