Proteins - Tertiary structure

Proteins - Tertiary structure

1. Protein Folding

   • Pathology
     • Alzheimers
     • Creuzdfelt - Jakobs
     • TSE
   • Mechanism
     • Agents that change conformation
       • Denaturation
         • Heat
       • Hydrophobic Interaction and H-bond disruption
         • pH
         • Organic solvents
         • Urea, Guanidinium chloride
         • Detergents
     • Experiments
       • Anfinsen's
     • Theories
       • Levinthal's paradox
       • Cumulative Selection
       • Hydrophobic collapse
     • Chacteristics
       • Coopertivity
       • Folding funnel

2. Globular Proteins

   • Myoglobin
     • Structure
     • Function

3. Protein Structure

   • Domains
   • Supersecondary structure
   • Intrinsically Unstructured