Protein Structure, Folding and Function

What this unit covers

The resources follow protein biochemistry from the building blocks upwards. Early material looks at amino acids, peptide bonds and primary structure. Later items move to alpha helices, beta sheets, tertiary and quaternary structure, then to folding, chaperones and what happens when folding goes wrong.

Where to start

Begin with the mind map Amino Acids and Proteins. It sets out the peptide bond, the native fold and secondary structure in one view. Then work through the flashcard deck Amino Acids, which lists residues such as aspartic acid, glutamic acid, tyrosine and cysteine.

Next, try the quiz Proteins (BIOC1001), which covers the main functional roles of proteins, such as binding and catalysis. After that, move on to Protein Folding- The Basics and Supersecondary Structures & Energy Changes.

Folding, chaperones and function

1. Read the mind map Protein folding to see how a sequence folds into a native structure that does its job.
2. Take Constituative Chaperones to test your grasp of DNAK and Hsp70 and the role of Hsp40.
3. Look at the mind maps on misfolding and the flashcards on amyloid diseases.
4. Finish with the haemoglobin quizzes and mind maps, which link structure to function.

Using quizzes and maps together

Read a mind map first to get the outline. Then take a quiz on the same topic and note what you missed. Go back to the map for those branches. Flashcards suit terms, amino acid names and short definitions. Teachers can pick a map or quiz to set as a starting point for a class.

Where it fits

This unit sits in the Structure and Function of Biomolecules strand of Biochemistry. Everything listed was made by GoConqr users, and it is free to open. Choose one quiz today and see which topics need another look.