antimicrobial agents

cell wall synthesis
1. beta-lactam
  1. penicillins
    1. natural penicillins
      1. Pen G (打针）
      2. Pen V （可口服）
      3. neisseria, haemophilus
    2. beta-lactamase resistant penicillins
      1. oxacillin, cloxacillin, dicloxacillin, Methicllin
        narrow & G +
        staphylococcal
    3. extended spectrum penicillins
      1. ampicllin ( testing)
      2. amoxicillin
      3. broad
    4. anti-pseudomonal penicillins
      1. carboxy penicllins
        carbenicliin, ticarcillin
      2. ureidopenicilllins
        azlocillin, mezlocillin, piperacillin
  2. cephalosporins
    1. 1st
      1. G+
      2. weak to G-
    2. 2nd
      1. not anti-pseudomonas
      2. G- bacilli
    3. 3rd
      1. enterobacteriaceae
      2. pseudomonas
    4. 4th
  3. orther beta-lactam antibiotics
    1. Aztreonam
      1. effective G-
      2. ineffective G+ , Anaerobes
      3. enterobacteriaceae
      4. pseudomonas
2. beta-lactamase inhibitors
  1. clavulanic acid
  2. sulbactam
3. Glycopeptides
  1. vancomycin
    1. hearing loss
    2. G +
  2. teicoplanin
4. carbapennems
  1. imipenem
    1. no effect on MRSA, VRE
    2. widest spectrum
5. extended spectrum beta-lactamases ( ESBL's)
protein synthesis
1. macrolide group
  1. erythromycin
2. chloramphenicol
  1. 氯霉素
3. tetracyclines
  1. terramycin,aureomycin,doxycycline, minocycline
4. aminoglycosides
DNA & RNA synthesis
1. quinolones
  1. fluoroquinolones
    1. ciprofloxacin, norfloxacin
  2. nalidixic acid
2. metronidazole
cell membrane function
1. polypeptides
  1. polymyxins
other metabolic process
1. sulfonamides
2. trimethoprim
3. nitrofurantoin

Próximo

Descrição

Resumo de Recurso

Semelhante

	Criado por dingwu.chang mais de 10 anos atrás