Immune System

dsandoval
Mind Map by dsandoval, updated 11 months ago
dsandoval
Created by dsandoval almost 4 years ago
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Science Board Review (Microbiology) Mind Map on Immune System, created by dsandoval on 02/29/2016.
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Immune System
1 Cell-mediated Immunity
1.1 T-cells
1.2 defense against infection
1.2.1 like mycobacterium tuberculosis
1.2.2 viral/fungal
1.3 Allergic response
1.3.1 Ex: poison oak
2 Antibody-mediated (Humoral) Immunity
2.1 B-Cells
2.2 defense against infection
2.2.1 opsonizes bacteria
2.2.2 neutralizes toxins/viruses
2.3 allergic response ex: Hay fever
2.4 autoimmunity
3 SPECIFICITY OF IMMUNE RESPONSE
3.1 Involves: recognition, activation, and response
3.2 may be natural (innate)/acquired (adaptive)
4 NATURAL IMMUNITY
4.1 Non-specific
4.2 not acquired from previous exposure
4.3 Does not improve after exposure
4.4 NO memory
4.5 Host defenses
4.5.1 Skin, mucous membranes
4.5.2 Natural killer cells
4.5.3 Phagocytosis
4.5.4 Inflammation
5 ACUIRED IMMUNITY
5.1 after exposure
5.2 improves w/ repeated exposure
5.3 Mediated by antibodies and T-cells
5.4 Long-term memory
5.5 Can be passive/active
6 ANTIGENS
6.1 Foreigness: Non-self
6.2 Dosage, route and timing of exposure
7 CELLS OF IMMUNE SYSTEM
7.1 Made up of Leukocytes
7.2 Granulocytes
7.2.1 Neutrophils, eosinophils, basophils
7.3 Lymphocytes
7.3.1 T-cells, B-cells, natural killer cells
7.4 Monocytes
7.4.1 precursor to macrophage
7.5 Dendritic Cells
7.5.1 APC's
7.5.2 key regulator
7.6 Produced in bone marrow
8 T Cells
8.1 65-80% of lymphocytes
8.2 Arise in bone marrow
8.3 T-cytotoxic cell
8.3.1 directly kill and attack
8.4 CD 4 T cell
8.4.1 produce cytokines, stimulate macrophages, NK cells, dendritic cell and other T-cell
9 B Cells
9.1 produce antibodies
9.2 Are APC's
9.3 Can form memory cells
10 MACROPHAGES
10.1 3 main funcitons
10.1.1 Phagocytosis
10.1.2 Antigen transportation
10.1.3 Cytokine production
11 Nk cells
11.1 kill viruses/tumor infected cells
11.2 Non-specific
11.3 kill w/o antibody
12 PMN's
12.1 most numerous WBC 60%
12.2 capable of phagocytosis
12.3 1st line of defense
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