TROPICAL LUNG

TROPICAL LUNG

1. HISTOPLASMOSIS

   • CLINICAL MANIFESTATIONS
     • Fever, chills, headache, muscle aches, dry cough, chest discomfort, fatigue
       • DIAGNOSIS
         • chest x-ray, histology and cultures - histological microscopic examination: diagnosis with intensity in patients with AIDS and extensive infections, Identification of H. capsulatum antigen is sensitive and specific in blood and urine

2. PARACOCCIDIODES

   • CLINICAL MANIFESTATIONS
     • Visceral: lesions -> hepatomegaly, splenomegaly and abdominal lymph nodes, abdominal pain.
       • Lymphatic: Cervical, supraclavicular, or axillary lymph nodes enlarge without pain
         • Mucocutaneous: infections on the face, nose and mouth with punctate lesions. Regional lymph nodes may enlarge, become necrotic, and shed necrotic material through the skin.
           • DIAGNOSIS
             • Culture, histopathology, observation of large yeasts: > 15 micrometers)

3. COCCIDIOIDOMICOSIS

   • CLINICAL MANIFESTATIONS
     • PRIMARY: fever, cough, chest pain, chills, sputum production, odynophagia, and hemoptysis. PROGRESSIVE: months or years later, nonspecific symptoms such as low-grade fever, anorexia, weight loss, and weakness.
       • DIAGNOSIS
         • Cultures, microscopic examination for C. immitis spherules, serologic tests, eosinophilia