Quiz
L4 Sympathetic nervous system and adrenergic neurotransmission
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Perguntas do quiz (10)
1Acetylcholine is the neurotransmitter at all ganglia, sympathetic or parasympathetic, and acts at nicotinic (N1) receptors.
- AVerdadeiro
- BFalso
2Most sympathetic post ganglionic nerve endings have [blank_start]adrenergic[blank_end] receptors (adrenoceptors), which come in 2 types, [blank_start]alpha and beta[blank_end]. There are subtypes [blank_start]1 and 2[blank_end] for both alpha and beta receptors.
Catecholamines act on several R types. Noradrenaline acts on [blank_start]alpha 1 and beta 1[blank_end]. Adrenaline acts on [blank_start]all adrenergic receptors[blank_end].- Aadrenergic
- Balpha and beta
- C1 and 2
- Dalpha 1 and beta 1 receptors
- Eall adrenergic receptors
3Select all the systems on which catecholamines have inhibitory actions.
- AHeart
- BVasculature to the skin, membranes and kidney
- CSalivary and sweat glands
- DGut
- EBronchial tree
- FVasculature of the skeletal muscle
4Sympathetic affects on the heart, via [blank_start]beta 1[blank_end] receptor stimulation:
• [blank_start]increased[blank_end] heart rate and contractility
• [blank_start]increased[blank_end] AV node conduction
• [blank_start]increased[blank_end] cardiac output
Sympathetic affects on the lungs, via [blank_start]beta 2[blank_end] receptor stimulation:
• [blank_start]decreased[blank_end] secretions
• [blank_start]increased[blank_end] airway diameter (relaxed bronchial muscle)
Sympathetic affects on the bladder:
• Relaxation of the detrusor muscle (via [blank_start]beta[blank_end] receptors)
• Contraction of the sphincter (via [blank_start]alpha 2[blank_end] receptors)- Aincreased
- Bdecreased
- Cincreased
- Ddecreased
- Eincreased
- Fdecreased
- Gbeta 1
- Hbeta 2
- Ibeta 2
- Jbeta 1
- Kdecreased
- Lincreased
- Mincreased
- Ndecreased
- Obeta
- Palpha
- Qalpha 2
- Ralpha 1
5Blood vessels express alpha, beta, dopamine, histamine, and muscarinic receptors. SNS activation releases noradrenaline, adrenaline, and dopamine.
Alpha 1 activation [blank_start]vasoconstricts[blank_end] vessels (arterioles) and [blank_start]decreases[blank_end] blood flow to unnecessary organs, so more blood can flow to where it's needed. Beta 2 [blank_start]vasodilates[blank_end] skeletal muscle beds and decreases overall vascular [blank_start]resistance[blank_end], increasing [blank_start]blood flow[blank_end] to muscles.- Avasoconstricts
- Bdecreases
- Cvasodilates
- Dresistance
- Eblood flow
6Dopamine (DA) has 3 different concentration-dependent mechanisms:
- Low [DA]: acts at [blank_start]dopamine 1[blank_end] receptors to dilate renal [blank_start]artery[blank_end], and increase [blank_start]kidney perfusion[blank_end].
- Med [DA]: stimulates [blank_start]beta 2[blank_end] receptors to dilate [blank_start]skeletal muscle bed[blank_end], and decreases systemic vascular [blank_start]resistance[blank_end]
- High [DA]: stimulates [blank_start]alpha 1[blank_end] receptors to cause vessel constriction and increase [blank_start]blood pressure[blank_end].
All levels of dopamine [blank_start]increase[blank_end] kidney perfusion.- Adopamine 1
- Bkidney perfusion
- Cartery
- Dbeta 2
- Eskeletal muscle bed
- Fresistance.
- Galpha 1
- Hblood pressure
- Iincrease
7Which of these is not a side effect of drugs that activate the SNS?
- ADecrease motility of large intestine, can cause constipation
- BCause pupillary dilation (may cause blurred vision)
- CCause piloerection (goose bumps)
- DCause perspiration (sweating)
- ECause dry mouth (may cause dysphagia)
8Sympathomimetic drugs are drugs that mimic the action of the [blank_start]sympathetic[blank_end] nervous system and are adrenergic [blank_start]agonists[blank_end]. They can be [blank_start]direct[blank_end] acting, and therefore selective for specific adrenergic receptors(or non-selective). They can also be [blank_start]indirect[blank_end] acting, by increasing the availability of [blank_start]noradrenaline/adrenaline[blank_end] to stimulate adrenoceptors.
- Aagonists
- Bsympathetic
- Cdirect
- Dindirect
- Enoradrenaline/adrenaline
9Entacapone and selegine are directly acting sympathomimetic drugs used to treat Parkinson's disease.
- AVerdadeiro
- BFalso
10Adrenergic [blank_start]antagonists[blank_end] are sympatholytics, i.e. they break the effects of the SNS. Many drugs [blank_start]interfere[blank_end] with the function of the SNS, and affect the [blank_start]physiology[blank_end] of sympathetically innervated organs. Several of these are important for the treatment of [blank_start]cardiovascular[blank_end] diseases(e.g. Beta blockers such as [blank_start]metoprolol[blank_end].)
- Aantagonists
- Binterfere
- Cphysiology
- Dcardiovascular
- Emetoprolol
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- O usuário eliminou as informações de disciplina Quiz sobre L4 Sympathetic nervous system and adrenergic neurotransmission, criado por Usuário eliminado em 14-04-2019.
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- Criado em 14 abr 2019 · atualizado em 26 mai 2019
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