Quiz
L28 Background hyperlipidemia
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Perguntas do quiz (7)
1Cholesterol is not water soluble, therefore it cannot circulate in the blood., and it needs to be packaged and carried by lipoproteins.
- AVerdadeiro
- BFalso
2High Density Lipoproteins (HDL) are 'good' cholesterol and we should have more than 1.0 mmol/L.
- AVerdadeiro
- BFalso
3Functions of lipoproteins:
Chylomicrons and VLDL: Deliver [blank_start]TAG[blank_end] to different cells in the body.
LDL: Delivers cholesterol to [blank_start]cells[blank_end] in the body where it can be used for the [blank_start]synthesis[blank_end] of membranes and [blank_start]steroid[blank_end] hormones.
HDL: Involved in reverse cholesterol transport – [blank_start]excess[blank_end] cholesterol is brought back to the [blank_start]liver[blank_end] by HDL, and [blank_start]removed[blank_end] from the body by the liver.- ATAG
- Bsynthesis
- Ccells
- Dsteroid
- Eexcess
- Fliver
- Gremoved
4Primary dyslipidaemias: Genetically determined but also influenced by [blank_start]environmental[blank_end] factors, i.e. familial hypercholesterolaemia is a genetic disorder where [blank_start]LDL[blank_end] is raised.
Secondary dyslipidaemias: Secondary to [blank_start]other[blank_end] disorders, or as a result of other [blank_start]drug[blank_end] therapies. Can be treated if the underlying cause is treated.- Aenvironmental
- BLDL
- Cother
- Ddrug
5Select all the medications (and not the conditions) that can cause secondary hypercholesterolaemia.
- ADiuretics and B-blockers
- BOral contraceptives
- CCorticosteroids
- DPregnancy
- EHypothyroidism
- FChronic renal failure
- GAlcohol abuse
6Pathophysiology of atherosclerosis:
1. Presence of [blank_start]hypercholestrolaemia[blank_end] and [blank_start]injury[blank_end] of endothelial lining of the coronary artery and/or other blood vessels.
2. Subendothelial migration of [blank_start]monocytes[blank_end] – accumulation of [blank_start]fatty[blank_end] streaks, containing lipid rich [blank_start]macrophages[blank_end] and [blank_start]T[blank_end]-cells.
3. Migration and proliferation of [blank_start]smooth[blank_end] muscle cells.
4. Smooth muscle cells + [blank_start]fibroblasts[blank_end] secrete collagen, elastin, proteoglycans, and glycoproteins – creating a [blank_start]fibrous[blank_end] cap around the necrotic tissue.
4. Presence of atherosclerotic [blank_start]plaques[blank_end] results in narrowing of blood vessels causing [blank_start]reduction[blank_end] of blood flow.
5. Plaque ruptures, causing formation of a [blank_start]thrombus[blank_end]- Ahypercholestrolaemia
- Binjury
- Cmonocytes
- Dfatty
- Emacrophages
- FT
- Gsmooth
- Hfibroblasts
- Ifibrous
- Jplaques
- Kreduction
- Lthrombus
7Reference ranges for lipids:
Total cholesterol: < [blank_start]4[blank_end] mmol/L
LDL cholesterol: < [blank_start]2.0[blank_end] mmol/L
HDL cholesterol: ≥ [blank_start]1.0[blank_end] mmol/L
Triglycerides: <[blank_start]1.7[blank_end]mmol/L- A4
- B2.0
- C1.0
- D1.7
Informações
- Descrição
- O usuário eliminou as informações de disciplina Quiz sobre L28 Background hyperlipidemia, criado por Usuário eliminado em 16-04-2019.
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- Usuário eliminado
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- English
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- Criado em 16 abr 2019 · atualizado em 26 mai 2019
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