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L28 Background hyperlipidemia

Deleted user 7 questions Updated 26 May 2019

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Questions in this quiz (7)

  1. 1Cholesterol is not water soluble, therefore it cannot circulate in the blood., and it needs to be packaged and carried by lipoproteins.
    1. ATrue
    2. BFalse
  2. 2High Density Lipoproteins (HDL)​ are 'good' cholesterol and we should have more than 1.0 mmol/L.
    1. ATrue
    2. BFalse
  3. 3Functions of lipoproteins:
    Chylomicrons and VLDL: Deliver [blank_start]TAG[blank_end] to different cells in the body​.
    LDL: Delivers cholesterol to [blank_start]cells[blank_end] in the body where it can be used for the [blank_start]synthesis[blank_end] of membranes and [blank_start]steroid[blank_end] hormones​.
    HDL: Involved in reverse cholesterol transport – [blank_start]excess[blank_end] cholesterol is brought back to the [blank_start]liver[blank_end] by HDL​, and [blank_start]removed[blank_end] from the body by the liver.
    1. ATAG
    2. Bsynthesis
    3. Ccells
    4. Dsteroid
    5. Eexcess
    6. Fliver
    7. Gremoved
  4. 4Primary dyslipidaemias: Genetically determined but also influenced by [blank_start]environmental[blank_end] factors, i.e. familial hypercholesterolaemia is a genetic disorder where [blank_start]LDL[blank_end] is raised.
    Secondary dyslipidaemias: Secondary to [blank_start]other[blank_end] disorders, or as a result of other [blank_start]drug[blank_end] therapies. Can be treated if the underlying cause is treated.
    1. Aenvironmental
    2. BLDL
    3. Cother
    4. Ddrug
  5. 5Select all the medications (and not the conditions) that can cause secondary hypercholesterolaemia.
    1. ADiuretics and B-blockers
    2. BOral contraceptives
    3. CCorticosteroids
    4. DPregnancy
    5. EHypothyroidism
    6. FChronic renal failure
    7. GAlcohol abuse
  6. 6Pathophysiology of atherosclerosis:
    1. Presence of [blank_start]hypercholestrolaemia[blank_end] and [blank_start]injury[blank_end] of endothelial lining of the coronary artery and/or other blood vessels.​
    2. Subendothelial migration of [blank_start]monocytes[blank_end] – accumulation of [blank_start]fatty[blank_end] streaks, containing lipid rich [blank_start]macrophages[blank_end] and [blank_start]T[blank_end]-cells.
    3. Migration and proliferation of [blank_start]smooth[blank_end] muscle cells​.
    4. Smooth muscle cells + [blank_start]fibroblasts[blank_end] secrete collagen, elastin, proteoglycans, and glycoproteins – creating a [blank_start]fibrous[blank_end] cap around the necrotic tissue​.
    4. Presence of atherosclerotic [blank_start]plaques[blank_end] results in narrowing of blood vessels causing [blank_start]reduction[blank_end] of blood flow​.
    5. Plaque ruptures, causing formation of a [blank_start]thrombus[blank_end]
    1. Ahypercholestrolaemia
    2. Binjury
    3. Cmonocytes
    4. Dfatty
    5. Emacrophages
    6. FT
    7. Gsmooth
    8. Hfibroblasts
    9. Ifibrous
    10. Jplaques
    11. Kreduction
    12. Lthrombus
  7. 7Reference ranges for lipids​:
    Total cholesterol: < [blank_start]4[blank_end] mmol/L​
    LDL cholesterol: < [blank_start]2.0[blank_end] mmol/L​
    HDL cholesterol: ≥ [blank_start]1.0[blank_end] mmol/L ​
    Triglycerides: <[blank_start]1.7[blank_end]mmol/L​
    1. A4
    2. B2.0
    3. C1.0
    4. D1.7

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Description
User has deleted their subject information Quiz on L28 Background hyperlipidemia, created by Deleted user on 16/04/2019.
Author
Deleted user
Language
English
Views
38
History
Created on 16 Apr 2019 · updated on 26 May 2019
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