Quiz
Clinical Immunology - Autoimmunity MCQs and Fill in the blanks
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Perguntas do quiz (25)
1Autoantibodies are normally present in the repertoire of the immune
system:- ATrue
- BWrong
2The functions of the immune system do not include distinguishing one's own from foreign antigens:
- ATrue
- BIncorrect
3Antinuclear antibodies (ANA) are positive in most patients with
systemic lupus erythematosus (SLE):- AYes
- BNo
4Sm and RNP are part of the group of extractable nuclear antigens that induce the formation of ANA:
- AYes
- BNo
5Autoantibodies to cytoplasmic antigens of neutrophils ANCA are not detected in Wegener's granulomatosis and microscopic polyangiitis:
- ATrue
- BIncorrect
6Which of the following mechanisms are involved in the development of autoimmune diseases
- AModification of its own antigen and its recognition as foreign to the immune system
- BDeficiency of suppressor T cells
- CAntigenic mimicry due to infection by microorganisms with cross reactive antigens
- DRelease of isolated (sequestered) antigens
- EAll answers are correct
7Systemic lupus erythematosus
- AAs caused by mutations in DNA
- BManifests itself with many symptoms and affects many organs
- CIs an example of a T-cell mediated disease
- DIs the result of the formation of immune complexes
- EAll answers are correct
8Vascular inflammation and glomerulonephritis induced by
autoantibodies are characteristic of:- AChronic granulomatous disease
- BAngioneurotic edema
- CSystemic lupus erythematosus
- DHemolytic anemia
- EThere is no correct answer
9Autoimmune hemolytic anemias occur most often by the type
of:- AAnaphylactic hypersensitivity reactions
- BCytotoxic hypersensitivity reactions
- CImmunocomplex hypersensitivity reactions
- DCell-mediated hypersensitivity reactions
- EThere is no correct answer
10Lymphocytic infiltration of the thyroid gland is characteristic
of:- ATuberculosis
- BPneumonia
- CHemolytic anemia
- DHashimoto's thyroiditis
- EThere is no correct answer
11The rheumatoid factor in the serum of a patient with rheumatoid arthritis is most often:
- AIgM reacting with an Fc fragment of endogenous IgG
- BIgM reacting with a Fab-fragment of IgG
- CIgE reacting with allergens
- DAntibody against DNA
- EAcute phase protein
12Which of the following methods is not used to detect rheumatoid factor in serum?
- ALatex agglutination
- BIndirect immunofluorescence
- CELISA
- DImmunoturbidimetry
- ENephelometry
13The following are used for ANA research:
- AThe direct immunofluorescence test
- BThe indirect immunofluorescence test
- CELISA and / or immunoblot
- DComplement fixation reaction
- ENeutralization
14Which of the following substrates are most commonly used for the determination of ANA with indirect immunofluorescence:
- ACryostatic section of rat liver
- BCryostatic section of rat kidney
- CCryostat section of rat stomach
- DHEp2 cell line
- EThere is no correct answer
15To prove autoimmune diseases of the thyroid gland are
examined- AAntinuclear antibodies
- BAnti-thyroglobulin antibodies
- CAnti-neutrophil cytoplasmic antibodies
- DAntibodies against thyroid peroxidase
- EAntibodies against pancreatic islet cells
16Rheumatoid arthritis develops by the mechanism
of [blank_start]IMMUNOCOMPLEX[blank_end] allergic reactions.- AIMMUNOCOMPLEX
17Autoantibodies to double-stranded DNA are found mainly in patients with [blank_start]SLE[blank_end].
- ASLE
18Patients with insulin-dependent diabetes mellitus usually have
antibodies to the [blank_start]ISLAND CELLS[blank_end] OF [blank_start]THE PANCREAS[blank_end].- AISLAND CELLS
- BTHE PANCREAS
19Anti-LKM, ANA and anti-smooth muscle antibodies are important studies in the diagnosis of [blank_start]AUTOIMMUNE HEPATITIS[blank_end].
- AAUTOIMMUNE HEPATITIS
20Detection of HLA-B27 antigen assists in the diagnosis
of [blank_start]ANKYLOSING SPONDYLITIS[blank_end].- AANKYLOSING SPONDYLITIS
21Antiphospholipid syndrome?
Answer: [blank_start]Anticardiolipin antibodies[blank_end]- AAnticardiolipin antibodies
22Myasthenia gravis?
Answer: [blank_start]Antibodies[blank_end] against [blank_start]acetylcholine receptors[blank_end]- AAntibodies
- Bacetylcholine receptors
23 Gluten enteropathy?
Answer: [blank_start]Antigliadin antibodies[blank_end]- AAntigliadin antibodies
24Pernicious anemia?
Answer: [blank_start]Autoantibodies[blank_end] against [blank_start]parietal[blank_end] cells of the [blank_start]stomach[blank_end] and [blank_start]intrinsic factor[blank_end]- AAutoantibodies
- Bparietal
- Cstomach
- Dintrinsic factor
25Primary biliary cirrhosis?
Answer: [blank_start]Antimitochondrial antibodies[blank_end]- AAntimitochondrial antibodies
Informações
- Descrição
- A2 clinical immunology Quiz sobre Clinical Immunology - Autoimmunity MCQs and Fill in the blanks, criado por suyog gurung em 17-06-2022.
- Autor
- suyog gurung
- Idioma
- English
- Visualizações
- 40
- Histórico
- Criado em 17 jun 2022 · atualizado em 17 jun 2022
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