Quiz
Lecture 30-36
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Questions in this quiz (15)
1FAD is synthesised from which vitamin?
- ARiboflavin (Vitamin B2)
- BRiboflavin (Vitamin B6)
- CNicotinate (Vitamin B6)
- DNicotinate (Vitamin B2)
2NAD+ is synthesised from which vitamin?
- ANicotinate (Vitamin B6)
- BNicotinate (Vitamin B2)
- CRiboflavin (Vitamin B6)
- DRiboflavin (Vitamin B2)
3In a hepatocyte, [blank_start]50[blank_end]kJ/mol of energy is required to convert one mole of [blank_start]ADP[blank_end] to one mole of [blank_start]ATP[blank_end]. This conversion is an [blank_start]endergonic[blank_end] reaction, however, to gain the energy to do this reaction, it couples ATP synthesis to the [blank_start]exergonic[blank_end] [blank_start]oxidation[blank_end] of fuel molecles
- A50
- B30
- C25
- DADP
- EATP
- Fendergonic
- Gexergonic
- Hoxidation
- Ireduction
4Which of the following is CORRECT
- AAcetyl CoA refers to CoA being attached to open chain molecules with 2 carbons
- BAcyl CoA refers to CoA being attached to open chain molecules with any number of carbons
- CAcetyl CoA refers to CoA being attached to open chain molecules with any number of carbons
- DAcyl CoA refers to CoA being attached to open chain molecules with 2 carbons
- ECoA is a co-enzyme that carries carbon molecules
- FCoA is a co-enzyme that acts as a reducing equivalent in oxidation reactions
- GCoA is an enzyme that carries carbon molecules
5Glycolysis is a [blank_start]catabolic[blank_end] pathway for the breakdown of [blank_start]glucose[blank_end] to [blank_start]pyruvate[blank_end]. Under [blank_start]aerobic[blank_end] conditions the product of glycolysis is converted to [blank_start]acetyl[blank_end]-CoA which then enters the [blank_start]citric[blank_end] [blank_start]acid[blank_end] [blank_start]cycle[blank_end]. Under [blank_start]anaerobic[blank_end] conditions the product is converted to [blank_start]lactate[blank_end] by the enzyme [blank_start]lactate[blank_end] [blank_start]dehydrogenase[blank_end]. This allows the regeneration of the coenzyme [blank_start]NAD[blank_end]+ from [blank_start]NADH[blank_end]. This NAD+ is important for the [blank_start]oxidation[blank_end] of glyceraldehyde-3-phosphate to 1,3 bisphosphoglycerate in the [blank_start]seventh[blank_end] reaction of glycolysis
- Acatabolic
- Bglucose
- Cpyruvate
- Daerobic
- Eacetyl
- Fcitric
- Gacid
- Hcycle
- Ianaerobic
- Jlactate
- Klactate
- Ldehydrogenase
- MNAD
- NNADH
- Ooxidation
- Pseventh
6The [blank_start]phosphorylation[blank_end] of glucose by [blank_start]hexokinase[blank_end] prevents the transport of glucose back [blank_start]out[blank_end] of the cell by the [blank_start]glucose[blank_end] transporter. It also decreases the [blank_start]concentration[blank_end] of glucose in the cell and helps ensure [blank_start]concentration[blank_end] gradient driven entry of glucose into cells.
- Ahexokinase
- Bphosphorylation
- Cout
- Dglucose
- Econcentration
- Fconcentration
7How do fatty acids get from adipose tissue to the peripheral tissues where they are used for energy?
- ATransported by serum albumin
- BDissolved in the plasma
- CVia facilitated transport via sodium
- DTransported by haemoglobin
8Where in the cell does fatty acid oxidation occur?
- AIn the mitochondrial matrix
- BIn the inner mitochondrial membrane
- CIn the cytosol
- DIn the outer mitochondrial matrix
9Fatty acids are activated for beta oxidation via attachment to [blank_start]CoA[blank_end], creating [blank_start]fatty[blank_end] [blank_start]acid[blank_end] [blank_start]CoA[blank_end] (or [blank_start]Acetyl[blank_end] [blank_start]CoA[blank_end]) this [blank_start]does[blank_end] require ATP
- ACoA
- Bfatty
- Cacid
- DCoA
- EAcetyl
- FCoA
- Gdoes
10Molecules are reversibly attached to which functional group on the CoA co enzyme
- AThe acetyl group
- BThe acyl group
- CThe SH group
- DThe carboxyl group
11The energy required to make fatty acid CoA comes from the [blank_start]hydrolysis[blank_end] of [blank_start]ATP[blank_end] to [blank_start]AMP[blank_end]
- Ahydrolysis
- BATP
- CAMP
12The first step of the citric acid cycle involves the [blank_start]condensation[blank_end] of acetyl CoA with oxaloacetate. The product of this reaction is citrate and is a [blank_start]six[blank_end] carbon molecule. This needs to be converted to a [blank_start]4[blank_end] carbon molecule and this is done by the removal of [blank_start]CO2[blank_end] through the process of [blank_start]oxidative[blank_end] [blank_start]decarboxylation[blank_end] which requires the cofactor [blank_start]NAD+[blank_end]. The product of these reactions is succinyl CoA which is converted to succinate. This reaction also involves the production of [blank_start]GTP[blank_end]. The next step in the pathway is the [blank_start]oxidation[blank_end] of succinate to fumarate by the enzyme succinate dehydrogenase which has the cofactor [blank_start]flavin adenine dinucleotide[blank_end] bound to it. This cofactor is derived from the vitamin [blank_start]riboflavin[blank_end] ([blank_start]B2[blank_end]). The enzyme succinate dehydrogenase is found in the [blank_start]inner[blank_end] [blank_start]mitochondrial[blank_end] [blank_start]membrane[blank_end] whilst the other citric acid cycle enzymes are found in the [blank_start]mitochondrial[blank_end] [blank_start]matrix[blank_end].
- Acondensation
- Bsix
- Cfour
- DCO2
- Eoxidative
- Fdecarboxylation
- GNAD+
- HGTP
- Ioxidation
- JFAD
- Kriboflavin
- LB2
- Minner
- Nmitochondrial
- Omembrane
- Pmitochondrial
- Qmatrix
13Aminotransferases transfer an [blank_start]amino[blank_end] group from an [blank_start]amino[blank_end] [blank_start]acid[blank_end] onto a [blank_start]keto[blank_end]-[blank_start]acid[blank_end] which can then be fed into [blank_start]catabolic[blank_end] (the process of breaking down macromolecules into simpler molecules) or [blank_start]anabolic[blank_end] (the process of synthesising macromolecules from simpler molecules) reactions. The enzyme required for this is [blank_start]pyridoxal[blank_end] [blank_start]phosphate[blank_end] which is derived from vitamin [blank_start]B6[blank_end], it [blank_start]accepts[blank_end] the amino group from the amino acid and [blank_start]transfers[blank_end] it to the keto-acid.
- Aamino
- Bamino
- Cacid
- Dketo
- Eacid
- Fcatabolic
- Ganabolic
- Hpyridoxal
- Iphosphate
- JB6
- Kaccepts
- Ltransfers
14The carbon skeletons remaining from amino acids can be oxidised further, [blank_start]aspartate[blank_end] goes to oxaloacetate (which feeds into the [blank_start]citric acid cycle[blank_end]), [blank_start]alanine[blank_end] goes to pyruvate (which under anaerobic conditions will end up as [blank_start]lactate[blank_end] via the enzyme [blank_start]lactate dehydrogenase[blank_end], or aerobic conditions will go to [blank_start]acetyl-CoA[blank_end], via the enzyme [blank_start]pyruvate dehydrogenase[blank_end]) and [blank_start]glutamate[blank_end] will go to α-ketoglutarate which feeds into the citric acid cycle.
- Aaspartate
- Bcitric acid cycle
- Calanine
- Dlactate
- Elactate dehydrogenase
- Facetyl-CoA
- Gpyruvate dehydrogenase
- Hglutamate
15Fill in the blanks for isolating mitochondria from cells
Isolate mitochondria rich cells (eg. [blank_start]liver[blank_end])
[blank_start]Homogenisation[blank_end] in buffered sucrose - grind them up to open up the contents into solution
[blank_start]Centrifuge[blank_end] Homogenate - separates out debris and nuclei (solids)
Centrifuge [blank_start]Supernatant[blank_end] - this is the liquid left after the first centrifuging
Isolate Mitochondria
Treat the isolated mitochondria with a mild [blank_start]detergent[blank_end] - this removes the [blank_start]outer[blank_end] membrane - The [blank_start]ETC[blank_end] still works, which shows that it occurs in the [blank_start]inner[blank_end] membrane- Aliver
- BHomogenisation
- CCentrifuge
- DSupernatant
- Edetergent
- Fouter
- GETC
- Hinner
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- Medicine (BIOC 192) Quiz on Lecture 30-36, created by Eva Bonning on 24/10/2017.
- Author
- Eva Bonning
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- English
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