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DF18 Capsules

Mer Scott 6 questions

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  1. 1Hard gelatin capsules:
    - 2 piece system; [blank_start]cap and body[blank_end]
    - can have [blank_start]different[blank_end] for identifying
    - traditionally made from [blank_start]gelatin[blank_end] (readily soluble at 37 degrees)
    - can be made from [blank_start]HPMC[blank_end]
    - filled with [blank_start]dry solids[blank_end]; power or granules
    Soft gelatin capsules:
    - 1 piece system; [blank_start]gelatin + water + plasticizer[blank_end]
    - transparent or [blank_start]opaque[blank_end], coloured, shaped
    - filled with [blank_start]liquids, suspensions, or semi-solids[blank_end]
    - used for [blank_start]poorly water soluble[blank_end] drugs, may have [blank_start]oily[blank_end] suspending agent
    - [blank_start]preservatives[blank_end] not required
    1. Acap and body
    2. Bgelatin + water + plasticizer
    3. Cdifferent colours
    4. Dgelatin
    5. EHPMC
    6. Fdry solids
    7. Gopaque
    8. Hliquids, suspensions, or semi-solids
    9. Ipoorly water soluble
    10. Joily
    11. Kpreservatives
  2. 2Hard get capsues can be filled by an automated process in a factory or extemporaneously at a hospital or community pharmacy.
    1. ATrue
    2. BFalse
  3. 3Extemporaneous compounding is useful(select all):
    1. ATo provide individualized dosing
    2. BWhen required dose or dosage form is not commercially available
    3. CWhen you have poor flow properties and need uniform weight and content
  4. 4To have drug release three things must occur. Select the correct 3 in the right order.
    1. ADisintegration of fill, disintegration of capsule, dissolution of fill
    2. BDisintegration of fill, disintegration of capsule, dissolution of capsule
    3. CDisintegration of capsule, disintegration of fill, dissolution of fill
    4. DDisintegration of capsule, disintegration of fill, dissolution of capsule
  5. 5A [blank_start]hydrophilic[blank_end] diluent aids dissolution of fill in [blank_start]hard gel[blank_end] capsules by [blank_start]increasing[blank_end] effective surface area for dissoultion.
    1. Ahydrophilic
    2. Bhydrophobic
    3. Chard gel
    4. Dsoft gel
    5. Eincreasing
    6. Fdecreasing
  6. 6Softegels can be in many forms. They can be swallowable/[blank_start]orally administered[blank_end], chewable, suckable, [blank_start]twist[blank_end] off, or [blank_start]meltable[blank_end] eg suppository. The rationale for choosing softgels is that they [blank_start]improve[blank_end] bioavailability, [blank_start]assure dose uniformity[blank_end] of low dose APIs, [blank_start]provide safe handling[blank_end] of high dose APIs, and constitute a [blank_start]stable[blank_end] dosage form for oxygen, light, and heat sensitive drugs.
    1. Aorally administered
    2. Btwist
    3. Cmeltable
    4. Dimprove
    5. Eassure dose uniformity
    6. Fprovide safe handling
    7. Gstable

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Description
PHCY211 (Formulation) Quiz on DF18 Capsules, created by Mer Scott on 01/05/2018.
Author
Mer Scott
Language
English
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