Quiz
MD1 - 2 Drug Stability
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Questions in this quiz (11)
1How much drug degradation is acceptable a) typically in pharmacopoeia specifications b) in calculations for this course?
- Aa) 1-2% b) 10%
- Ba) 0.5-1% b) 5%
- Ca) 5-10% b) 15%
2Label the conc. vs time graphs.
- A1st order
- B0 order
32nd order rate constant units are time^-1.conc^-1 so [blank_start]s^-1 * M^-1[blank_end].
1st or apparent 1st order rate constant units are time^-1 so [blank_start]s^-1[blank_end].
0 order rate constant units are conc.time^-1 so [blank_start]M * s^-1[blank_end].- As^-1 * M^-1
- Bs^-1
- CM * s^-1
4Select the correct equation for 0 order reactions.
- A[D] = [D]o - k(obs) * t
- Bln[D] = ln[D]o - k(obs) * t
- C[D] = [D]o * e^(k(obs) * t)
5Which equation would you use to find the half life of a 1st order reaction?
- At0.5 = 0.693 / k(obs)
- Bt0.5 = 0.105 / k(obs)
- Ct0.5 = 0.693 * [D]o / k(obs)
- Dt0.5 = 0.5 * [D]o / k(obs)
6Which equation would you use to find the shelf life of a drug with 1st order reaction?
- At0.9 = 0.105 / k(obs)
- Bt0.9 = 0.683 / k(obs)
- Ct0.9 = [D]o * 0.9 / k(obs)
- Dt0.9 = [D]o * 0.1 / k(obs)
7Which equation would you use to find the half life of a drug with a 0 order reaction?
- At0.5 = [D]o * 0.5 / k(obs)
- Bt0.5 = [D]o * 0.1 / k(obs)
- Ct0.5 = [D] * 0.5 / k(obs)
- Dt0.5 = [D] * 0.1 / k(obs)
8Which equation would you use to find the shelf life of a drug with a 0 order reaction?
- At0.9 = [D]o * 0.1 / k(obs)
- Bt0.9 = [D]o * 0.9 / k(obs)
- Ct0.9 = [D]o * 0.5 / k(obs)
9Apparent 1st order reactions describe a situation where one of the reactants is present in large excess or does not effect the overall reaction.
- ATrue
- BFalse
10t0.9 (0 order) is independent of concentration, while t0.5 (1st order) depends on the initial drug concentration.
- ATrue
- BFalse
11If [D]solution and [D]solid are in equilibrium then [D] solution is replaceable and constant.
- ATrue
- BFalse
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- PHCY211 (Medicines) Quiz on MD1 - 2 Drug Stability, created by Mer Scott on 10/05/2018.
- Author
- Mer Scott
- Language
- English
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