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Neurobiology of Addiction

Matthew Coulson 9 questions Updated 4 Oct 2018

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Questions in this quiz (9)

  1. 1The reward pathway, in the most basic sense, begins in the floor of the midbrain at the [blank_start]ventral tegmental area[blank_end] (clue: VTA), which then projects to the [blank_start]nucleus accumbens[blank_end]. This structure then projects finally to the [blank_start]prefrontal[blank_end] cortex.
    1. Aventral tegmental area
    2. Bnucleus accumbens
    3. Cprefrontal
  2. 2The reward pathway is also known as the
    1. AMesolimbic Pathway
    2. BMesocortical Pathway
    3. CNigrostriatal Pathway
    4. DTuberoinfundibular Pathway
  3. 3The mesolimbic pathway is one of the four ...
    1. ADopaminergic Pathways
    2. BAdrenergic Pathways
    3. CGlutamatergic Pathways
  4. 4In terms of the nucleus accumbens, overexpression of which gene transcription factor is thought to be the main influencer of addiction?
    1. AΔFosB
    2. BΔJunD
    3. CcAMP
    4. DCREB
    5. ENFκB
  5. 5Patients showing addictive behaviours tend to have a preserved insight; they know they are unwell.
    1. ATrue
    2. BFalse
  6. 6Dopamine release usually has the ability to update info and set new goals in the prefrontal cortex, thus having the ability to avoid compulsive repetition of a behaviour. Addictive drugs provide a potent dopamine signal which disrupts the normal dopamine learning pathway in the prefrontal cortex.
    1. ATrue
    2. BFalse
  7. 7On average, those who start experimenting with drugs earlier in life tend to have a shorter relationship with drugs.
    1. ATrue
    2. BFalse
  8. 8Which part of the frontal cortex concerns the following:
    Emotion and reward in decision making; hyperactivity of this area during addiction behaviour represents craving
    1. AOrbitofrontal Cortex
    2. B‎Ventrolateral Prefrontal Cortex
    3. C‎Dorsolateral Prefrontal Cortex
  9. 9In [blank_start]non-addicted[blank_end] brains, areas such as the Anterior Cingulate Gyrus send inhibitory signals to the orbitofrontal cortex and thus the sensation of craving [blank_start]does not[blank_end] occur.
    In [blank_start]addicted[blank_end] brains, the nucleus accumbens sends inhibitory signals to areas such as the Anterior Cingulate Gyrus so that the inhibitory signals are not sent to the Orbitofrontal cortex and thus the sensation of craving [blank_start]does[blank_end] occur
    1. Anon-addicted
    2. Baddicted
    3. Caddicted
    4. Dnon-addicted
    5. Edoes not
    6. Fdoes
    7. Gdoes
    8. Hdoes not

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Description
Neurobiology of Addiction lecture given on 05/10/2018
Language
English
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112
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Created on 4 Oct 2018 · updated on 4 Oct 2018
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