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Neurologic and Neuromuscular Drugs

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Quiz 3
Jennifer Keough
Quiz by Jennifer Keough, updated more than 1 year ago
Jennifer Keough
Created by Jennifer Keough over 5 years ago
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Resource summary

Question 1

Question
Centrally-acting skeletal muscle relaxants are basically Central Nervous System depressants.
Answer
  • True
  • False

Question 2

Question
Direct-acting skeletal muscle relaxants affect:
Answer
  • a. skeletal muscle
  • b. cardiac muscle
  • c. smooth muscle
  • d. all the above are true

Question 3

Question
Neuromuscular blocking drugs work by:
Answer
  • a. disrupting nerve impulses at motor end plates
  • b. disrupting nerve impulses at post-synaptic neurons
  • c. both the above are true

Question 4

Question
Depolarizing neuromuscular blocking drugs are derived from curare alkaloids.
Answer
  • True
  • False

Question 5

Question
The ________________ is that area where a terminal nerve ending innervates a muscle.
Answer
  • a. motor end plate
  • b. synaptic cleft
  • c. both the above are true

Question 6

Question
Curare alkaloids:
Answer
  • Paralyze the diaphragm preventing breathing
  • cross the blood-brain-barrier
  • make one go unconscious immediately
  • compete with phosphorus involved in muscle contractions

Question 7

Question
The antidote for curare alkaloids are ____________ drugs.
Answer
  • anti-cholinesterase
  • cholinesterase

Question 8

Question
Depolarizing neuromuscular blocking drugs cannot be inactivated by cholinesterase.
Answer
  • True
  • False

Question 9

Question
Succinylcholine is metabolized slower than acetylcholine, resulting in:
Answer
  • Longer muscle paralysis
  • Shorter muscle paralysis
  • Succinylcholine has nothing to do with muscle paralysis

Question 10

Question
What are the movement disorders associated with Parkinson's disease?
Answer
  • a. Muscle rigidity
  • b. Akinesia
  • c. Tremors at rest
  • d. Posture/balance disturbances
  • e. a and d are correct
  • f. c and d are correct
  • g. All the above are correct

Question 11

Question
Akinesia is the absence of:
Answer
  • the power of voluntary movement
  • the ability to think
  • diaphragmatic movement
  • the ability of speech

Question 12

Question
The 2 types of therapy for Parkinson's disease are _____________ and ______________ drugs.
Answer
  • anti-cholinergic; dopaminergic
  • anti-cholinergic; anti-cholinesterase
  • cholinergic; dopaminergic
  • cholinergic; anti-cholinersterase

Question 13

Question
Anti-cholinergic drugs inhibit acetylcholine action at parasympathetic receptors.
Answer
  • True
  • False

Question 14

Question
Too much acetylcholine will excite the CNS causing parkinsonian tremor.
Answer
  • True
  • False

Question 15

Question
Dopaminergic drugs act on the brain to improve motor function.
Answer
  • True
  • False

Question 16

Question
Dopaminergic drugs act on the brain to improve motor function.
Answer
  • True
  • False

Question 17

Question
Lavodopa can convert to dopamine:
Answer
  • a. before crossing the blood-brain-barrier
  • b. after crossing the blood-brain-barrier
  • c. both the above are true

Question 18

Question
COMT stands for:
Answer
  • a. Catechol-O-methyltransferase
  • b. Catechol-OH-methyltransacetylase
  • c. Catecholamine-O-methyltransacetylase
  • d. none of the above are correct

Question 19

Question
Another name of 5-HT1-receptor agonists is triptans.
Answer
  • True
  • False

Question 20

Question
5-HT1-receptor agonists and ergotamine preparations are both used in the treatment of:
Answer
  • migraines
  • musculoskeletal issues
  • seizures
  • Parkinson's disease

Question 21

Question
Depolarizing neuromuscular blocking drugs act like ____________.
Answer
  • acetylcholine
  • norepinephrine
  • epinephrine
  • dopamine

Question 22

Question
Physical and psychological dependence are major adverse effects of direct-acting skeletal muscle relaxants.
Answer
  • True
  • False

Question 23

Question
Direct-acting skeletal muscle relaxants interfere with ___________ ions involved in skeletal muscle contraction:
Answer
  • sodium
  • calcium
  • magnesium
  • phosphorus

Question 24

Question
Parkinson's disease:
Answer
  • a. has a deficiency of dopamine
  • b. has an excess of acetylcholine
  • c. is a movement disorder
  • d. all the above are true

Question 25

Question
Another name for anti-cholinergic drugs is ____________ drugs.
Answer
  • parasympatholytic
  • sympatholytic

Question 26

Question
COMT inhibitors are reversible.
Answer
  • True
  • False

Question 27

Question
Triptans are used to treat:
Answer
  • seizures
  • musculoskeletal issues
  • Parkinson's disease
  • migraines

Question 28

Question
Abortive anti-migraine drugs are designed to stop a migraine:
Answer
  • a. after it starts
  • b. before it starts
  • c. both the above are correct
  • d. neither of the above are correct

Question 29

Question
Levodopa needs passage through the blood-brain-barrier to become effective.
Answer
  • True
  • False

Question 30

Question
Carbidopa enhances the effectiveness of Levodopa by preventing its peripheral conversion to dopamine.
Answer
  • True
  • False

Question 31

Question
COMT inhibitors are used in Parkinson patients when the initial therapy begins to wear off.
Answer
  • True
  • False

Question 32

Question
Contraindication for taking triptans includes:
Answer
  • a. Ischemic
  • b. Cerebrovascular
  • c. Coronary artery disease
  • d. All the above are correct

Question 33

Question
Anti-cholinergic drugs inhibit acetylcholine action at sympathetic receptors.
Answer
  • True
  • False

Question 34

Question
For epilepsy and seizures a(an) ______________ drug is usually recommended.
Answer
  • a. anti-migraine
  • b. COMT inhibitor
  • c. dopaminergic
  • d. anti-convulsant

Question 35

Question
To have a higher conversion to dopamine after passing through the blood-brain-barrier, one needs to take ______________.
Answer
  • a. Levodopa
  • b. Carbidopa
  • c. Levodopa and Carbidopa
  • d. None of the above drugs have anything to do with dopamine

Question 36

Question
Anti-convulsant drugs:
Answer
  • a. Stabilize nerve cells from over excitement
  • b. Elevate seizure thresholds
  • c. Inhibit neuromuscular transmission
  • d. Increase GABA
  • e. All the above are correct

Question 37

Question
The neurotransmitter released at motor end plates is:
Answer
  • a. Norepinephrine
  • b. Dopamine
  • c. Acetylcholine
  • d. Epinephrine

Question 38

Question
The effectiveness of ergotamine preparations is increased by drinking coffee.
Answer
  • True
  • False
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