Quiz
General pathology
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Questions in this quiz (20)
1A tumour has to grow larger than 1-2mm. What supportive mechanism will be required? Identify the correct statement.
- AAngiogenesis
- BApplication of promotors
- CApplication of initiators
- DGrowth factors
- ESecondary mutations
2Genes that promote autonomous cell growth in cancer cells are called as;
- AAnti-apoptotic genes
- BDNA repair genes
- COncogenes
- DTumour suppressor genes
- ERNA repair genes
3A patient of adenomacarcinoma of prostate is treated by the oncologist and is under regular follow-up. Which serum tumour marker will help in determining tumour recurrence
- ACA 125
- BCEA
- CPSA
- DProlactin
4Individuals who have hereditary predisposition to cancer, the detection of mutated alleles may allow the patient and physician to devise an aggressive screening program and consider the option of prophylactic surgery and counseling of relatives at risk. This is not seen in germ line mutation of:
- AAPC
- BBRCA1
- CBRCA2
- DKRAS
- Enone of the above
5The incidence of carcinoma of cervix has fallen down in West because of the effective screening program for early detection of premalignant lesions. Select one diagnostic modality for screening of cervical cancer in your population
- ACT scan
- BPap smear
- CPCR
- DSerum CA-125 levels
- Ecervical x-ray
6In evolution of colorectal cancers through adenoma-carcinoma sequence identify mutation of gene which is an early event.
- AAPC
- BP53
- CKRAS
- DSMAD1
- EBRACA!
7The earliest mechanism for increased vascular permeability in acute inflammatory response is:
- AIncreased transcytosis
- BDirect endothelial cell damage
- CLeucocyte mediated endothelial injury
- DCytoskeletal reorganization
- EEndothelial cell contraction
8An athelete develops acute throat infection. In addition to local acute inflammatoryt changes he develops fever and malaise. These constitutional symptoms are mediated by
- AHistamine
- BIL-1 & TNF
- CC3a
- DProstacyclin
- EThromboxane A2
9 A 55-year-old woman has been treated in the hospital for pancreatitis for the past three weeks. She is examined one morning on rounds and found to have a swollen right leg. It is tender to palpation posteriorly but is not warm. This condition is most likely to be the result of which of the following vascular complications?
- AVenous thrombosis
- BSeptic embolization
- CCongestive heart failure
- DCellulitis
- EInfarction
10Causes of localized Oedema include:
- ALoss of proteins through kidneys
- BLoss of proteins through gut
- CObstruction of lymphatics
- DCongestive cardiac failure
- Enone of the above
11Type III hypersensitivity reaction develops when:
- AAntigens are trapped in macrophages and cannot be cleared
- BAntibody binds to either self antigen or foreign antigen on cells
- CAn IgE antibody response is directed against harmless environmental antigens
- DImmune complexes are formed in large quantities and cannot be cleared
- EIgM is produced as a part of primary humoral response
12After a minor trauma to the big toe, a child develops painful swelling over it which is red warm and tender. The swelling is fluctuant. The surgeons diagnose it to be an abscess which is
- AAn area of chronic inflammation with granulomas in it
- BA localized collection of transudate
- CA localized collection of granulation tissue
- DAn area of collagen deposition
- EA localized collection of pus
13The difference between GHON COMPLEX and GHON LESION is
- APrimary lesion + Draining Lymph nodes in Ghon complex.
- BReinfection or without involvement of draining lymph nodes in Ghon complex.
- CIn Ghon lesions draining lymph nodes are involved.
- DIn Ghon complex draining lymph nodes are not involved.
- EIn Ghon lesion draining lymph nodes are involved.
14A 40 years old male presents to his physician with maculopapular rashes on his palm and soles, low grade fever, malaise, anorexia, weight loss, headache and myalgias. Examination reveals generalized lymphadenopathy.On further questioning he gives a history of non tender ulcer in his groin regions 2 months prior to his present symptoms what is the most likely organism responsible:
- ABorellia recurrentis
- Bleptospira interrogans
- CBorellia burgdoferri
- DHIV
- Etreponema pallidum
15A young man of 20 , got a lacerated wound on his left arm , stiched-1week later surures were remained-healing continued but the site became disfigured by prominent raised irregular nodular scar , in next 2 month which of the following best describes the process :
- AOrganization
- BDehiscence
- CResolution
- DKeloid formation
- ESecondary union
16the growth factor elaborated by macrophages , which recruits macrophages and fibroblasts to wound site and induces all steps in angiogenesis :
- Avascular endothelial growth factor
- Bfibroblast growth factor
- Cepithelial growth factor
- Dplatelet derived growth factor
17the most characteristic features of granulation tissues is that :
- Agrowth of fibroblast and new capillaries
- Bcharacter of the exaudate
- Cgranular scar that results
- Dpresence of momocytes and fibroblasts
18which of the following is a reversible changes :
- Apyknosis
- Bkaryolysis
- Cswelling of endoplasmic reticulum
- Dkaryorrhexis
19after initiation of an acute inflammatory process third in a sequence of changes in vascular flow is :
- Avasoconstriction
- Bredness
- Cleukocytic migrationn
- Dvasodilatation
20which of the following types of necrosis is most commonly associated with ischemic injury :
- Acoagulative necrosis
- Bliquifactive necrosis
- Ccaseous necrosis
- Dfat necrosis
Information
- Description
- multiple choice question on general pathology for 3rd year medical students
- Author
- Nada Medhat
- Language
- English
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