Breast Pathology I

Matthew Coulson
Quiz by Matthew Coulson, updated more than 1 year ago
Matthew Coulson
Created by Matthew Coulson over 2 years ago
7
1

Description

Breast pathology I lecture given on 07/01/2019

Resource summary

Question 1

Question
Match the biopsy techniques to their field: Fine Needle Aspiration = [blank_start]Cytopathology[blank_end] Core Needle Biopsy = [blank_start]Histology[blank_end]
Answer
  • Histology
  • Cytopathology

Question 2

Question
Which is most commonly utilised mode of biopsy in terms of retrieving breast tissue?
Answer
  • Fine Needle Aspiration
  • Core Needle Biopsy

Question 3

Question
[blank_start]Histological[blank_end] biopsy techniques allow a clinician to assess whether a malignant cancer is in situ or invasive. This is not available when utilising a [blank_start]Cytological[blank_end] technique of biopsy.
Answer
  • Histological
  • Cytological
  • Cytological
  • Histological

Question 4

Question
Excessive growth of the breasts during puberty is known as juvenile breast [blank_start]hypertrophy[blank_end]
Answer
  • hypertrophy

Question 5

Question
Enlargement of a man's breasts, usually due to hormone imbalance or hormone therapy is known as [blank_start]gynaecomastia[blank_end]
Answer
  • gynaecomastia

Question 6

Question
Gynaecomastia involves ductal growth within the breast [blank_start]without[blank_end] associated lobular development
Answer
  • without
  • with

Question 7

Question
Excessive cannabis use is a known cause of gynaecomastia
Answer
  • True
  • False

Question 8

Question
Having [blank_start]liver[blank_end] disease is a risk factor for developing gynaecomastia
Answer
  • liver
  • kidney
  • heart
  • crohn's

Question 9

Question
Women between the ages of 20-50 (majority 40-50) commonly develop benign breast lumps due to fibrous tissue aggregates in an area of the breast. What is this known as? [blank_start]Fibrocystic change[blank_end]
Answer
  • Fibrocystic change

Question 10

Question
Fibrocystic change occurs in around [blank_start]one third[blank_end] of women at some point in their lifetime (typically 40-50)
Answer
  • one third
  • a half
  • one quarter
  • three quarters

Question 11

Question
Fibrocystic changes in women typically subside or reduce following menopause.
Answer
  • True
  • False

Question 12

Question
Fibrocystic changes are usually painless.
Answer
  • True
  • False

Question 13

Question
What is the difference between cytology and histology? [blank_start]Cytology[blank_end] = Study of individual cells [blank_start]Histology[blank_end] = Study of tissues
Answer
  • Histology
  • Cytology

Question 14

Question
Which two of the following are known risk factors for breast cancer development?
Answer
  • Early menarche (periods starting early, under age 12)
  • Late menarche (periods starting late)
  • Early menopause
  • Late menopause

Question 15

Question
Despite being associated with breast cancer, early menarche and late menopause are also associated with fibrocystic changes.
Answer
  • True
  • False

Question 16

Question
Which, if any, of the following conditions is painful? Fibrocystic Change: [blank_start]Painful[blank_end] Fibroadenoma: [blank_start]Painless[blank_end]
Answer
  • Painless
  • Painful
  • Painful
  • Painless

Question 17

Question
Fibrocystic change usually occurs as development of a single solitary mass.
Answer
  • True
  • False

Question 18

Question
What is the typical management of fibrocystic change?
Answer
  • Exclude malignancy and reassure patient
  • Immediate excision
  • Topical steroid to reduce the mass

Question 19

Question
Fibrocystic changes are known to commonly develop into breast cancer
Answer
  • True
  • False

Question 20

Question
Name the condition: "A circumscribed benign lesion composed of tissues normal to the breast (adipose, glandular and connective) but organised in an abnormal proportion or distribution" [blank_start]Hamartoma[blank_end]
Answer
  • Hamartoma

Question 21

Question
Fibroadenomas typically occur as a single solitary lesion.
Answer
  • True
  • False

Question 22

Question
Occurs as multiple lesions: [blank_start]Fibrocystic Change[blank_end] Occurs as single lesion: [blank_start]Fibroadenoma[blank_end] Typically painless: [blank_start]Fibroadenoma[blank_end] Typically painful: [blank_start]Fibrocystic Change[blank_end]
Answer
  • Fibroadenoma
  • Fibrocystic Change
  • Fibroadenoma
  • Fibrocystic Change
  • Fibrocystic Change
  • Fibroadenoma
  • Fibrocystic Change
  • Fibroadenoma

Question 23

Question
Fibroadenoma is more common in women of asian origin.
Answer
  • True
  • False

Question 24

Question
Fibroadenomas most commonly present in a woman's [blank_start]30s[blank_end]
Answer
  • 30s
  • 20s
  • 40s

Question 25

Question
Fibroadenomas are typically [blank_start]mobile[blank_end] lesions
Answer
  • mobile
  • immobile

Question 26

Question
When seeing woman with suspicious breast lesions, their age defines which type of scan they should have: A woman under the age of [blank_start]40[blank_end] should have [blank_start]an Ultrasound Scan[blank_end] A woman over the age of [blank_start]40[blank_end] should have [blank_start]a Mammogram[blank_end]
Answer
  • a Mammogram
  • an Ultrasound Scan
  • an Ultrasound Scan
  • a Mammogram
  • 40
  • 30
  • 50
  • 40
  • 30
  • 50

Question 27

Question
How are fibroadenomas typically managed?
Answer
  • Exclude malignancy and reassure patient
  • Immediate excision once diagnosis is made
  • Topical steroid to reduce the mass

Question 28

Question
Malignant breast cancers are typically solid and fixed within the breast.
Answer
  • True
  • False

Question 29

Question
[blank_start]Sclerosing Adenosis[blank_end] is a benign proliferative condition of the terminal duct lobular units characterised by an increased number of acini and their glands. This may cause a mass or calcification within the breast which can be mistaken for a breast cancer.
Answer
  • Sclerosing Adenosis

Question 30

Question
Sclerosing Adenosis should be excised as soon as possible following diagnosis due to the risk that it may undergo malignant change.
Answer
  • True
  • False

Question 31

Question
A complex sclerosing lesion of the breast is a benign breast lesion that can radiologically mimic malignancy. Clinically, this is known as a [blank_start]radial[blank_end] scar
Answer
  • radial

Question 32

Question
A [blank_start]Radial Scar[blank_end] is more serious as it can progress to invasive carcinoma. It should therefore the excised or at least extensively sampled.
Answer
  • Radial Scar
  • Sclerosing Adenosis

Question 33

Question
Which two of the following biopsy techniques are typically utilised in the diagnosis of a radial scar?
Answer
  • Core Needle Biopsy
  • Vacuum Needle Biopsy
  • Fine Needle Aspiration

Question 34

Question
Which of the following conditions most commonly occurs due to local trauma, for example a seat belt injury?
Answer
  • Fat necrosis
  • Duct ectasia
  • Acute mastitis

Question 35

Question
Which anticoagulant drug is also known to cause fat necrosis of the breast? [blank_start]Warfarin[blank_end]
Answer
  • Warfarin

Question 36

Question
Which of the following conditions is very highly associated with a long smoking history?
Answer
  • Fat necrosis
  • Duct ectasia
  • Acute mastitis

Question 37

Question
Which inflammatory breast condition is associated with smoking and causes fistulas to open up around the nipple? [blank_start]Duct ectasia[blank_end]
Answer
  • Duct ectasia

Question 38

Question
Duct ectasia is typically very painful and produces bloody and/or purulent discharge
Answer
  • True
  • False

Question 39

Question
Which 3 of the following features typically occur as part of duct ectasia?
Answer
  • Bloody/purulent discharge
  • Pain
  • Nipple retraction
  • Eczema of the nipple
  • Lactational discharge

Question 40

Question
Which three of the following are common interventions for duct ectasia?
Answer
  • Treat any underlying infection
  • Referral to smoking cessation service
  • Excise the affected subareolar ducts
  • Apply topical steroid to suppress the inflammation - fistulas will close with time and positive lifestyle choices
  • Mastectomy

Question 41

Question
Which 2 of the following bacteria are typically involved in mastitis due to breast-feeding?
Answer
  • Staph Aureus
  • Strep Pyogenes
  • Strep Viridans
  • Staph Epidermidis
  • Klebsiella Pneumoniae

Question 42

Question
Phyllodes Tumours are, in the most part, benign tumours although they can become malignant.
Answer
  • True
  • False

Question 43

Question
Phyllodes Tumours are typically removed via a laparoscopic operation
Answer
  • True
  • False
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