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Basic NeuroScience Quiz

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This is a Quiz opposed to Flashcards in order to see how the different "apps" on this website work.
Eleanor garvey
Quiz by Eleanor garvey, updated more than 1 year ago
Eleanor garvey
Created by Eleanor garvey over 4 years ago
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Resource summary

Question 1

Question
24. Which one of the following neurotransmitters is not associated with the inhibition of aggressive behavior?
Answer
  • A. Dopamine
  • B. Norepinephrine
  • C. Serotonin
  • D. γ-Aminobutyric acid (GABA)
  • E. Glycine

Question 2

Question
41. Glutamate is not:
Answer
  • One of the two major amino acid neurotransmitters
  • An inhibitory neurotransmitter
  • Involved in learning and memory
  • The primary neurotransmitter in cerebellar granule cells
  • A precursor of GABA

Question 3

Question
46. Which one of the following statements is true regarding neurotransmitters and anxiety?
Answer
  • GABA has nothing to do with anxiety
  • GABA, norepinephrine, and serotonin are associated with anxiety in some way
  • Dopamine, glutamate, and histamine are associated with anxiety in some way
  • Only acetylcholine is associated with anxiety
  • Anxiety can be treated with injection of epinephrine

Question 4

Question
93. A 25-year-old man is brought to see you because of a change in personality following a boating accident. He fell off of his boat and landed head first on the dock. He was previously friendly, happy, and high-functioning. Now his speech is pressured and his mood is labile. He has been irresponsible at work and has been fired from his job. His memory is intact. Which one of the following brain areas did he damage?
Answer
  • Temporal lobe
  • Occipital lobe
  • Basal ganglia
  • Substantia nigra
  • Frontal lobe

Question 5

Question
97. Which one of the following brain areas is characteristically serotonergic?
Answer
  • Ventral tegmental area
  • Substantia nigra
  • Nucleus accumbens
  • Cerebellum
  • Raphe nuclei

Question 6

Question
99. A patient comes into the emergency room high on cocaine. Which one of the following brain regions would you expect to be most active in terms of the reward he is experiencing from the drug?
Answer
  • Neocortex
  • Substantia nigra
  • Nucleus accumbens
  • Locus ceruleus
  • Raphe nuclei

Question 7

Question
3. Which one of the following statements is not true regarding receptors?
Answer
  • Seven-transmembrane-domain receptors require G proteins to open ion channels
  • In the ligand-gated ion channel receptor, the channel is built into the complex that binds the ligand
  • Seven-transmembrane-domain receptors have an external NH(2) terminal end and an intracellular COOH terminal end
  • Nerve growth factor (NGF) and brain-derived neurotropic factor (BDNF) bind to seven-transmembrane domain-receptors
  • Hormones may diffuse into the cell and bind cytoplasmic receptors, which leads to influence over gene expression

Question 8

Question
33. Which of the following is true regarding norepinephrine (NE) and/or the locus ceruleus?
Answer
  • NE is synthesized in the locus ceruleus
  • Dopamine is synthesized in the locus ceruleus, NE in the dorsal raphe nuclei
  • Acetylcholine is synthesized with NE in the substantia nigra
  • 5-HT is synthesized in the locus ceruleus
  • The locus ceruleus is the site of the formation of serotonin

Question 9

Question
35. Which one of the following receptor types is associated with weight gain and sedation?
Answer
  • 5-HT 2A
  • α1
  • 5-HT 1A
  • H1
  • M1

Question 10

Question
37. Which of the following is not a biogenic amine neurotransmitter?
Answer
  • Dopamine
  • γ-Aminobutyric acid (GABA)
  • Epinephrine
  • Acetylcholine
  • Serotonin

Question 11

Question
44. Melatonin is a neuronal hormone that promotes sleep and is produced in the brain by the:
Answer
  • Pineal gland
  • Anterior pituitary gland
  • Posterior pituitary gland
  • Hypothalamus
  • Thalamus

Question 12

Question
91. Which one of the following is not a second messenger?
Answer
  • Adenylyl cyclase
  • cGMP
  • Ca2+
  • cAMP
  • Inositol triphosphate (IP3)

Question 13

Question
95. Which one of the following receptor subtypes is associated with the neurotransmitter glutamate?
Answer
  • Nicotinic
  • Muscarinic
  • α1
  • α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)
  • GABA

Question 14

Question
97. Which one of the following statements is true regarding excitatory neurotransmitters?
Answer
  • They open anion channels that depolarize the cell membrane and increase the likelihood of generating an action potential
  • They open cation channels that hyperpolarize the cell membrane and increase the likelihood of generating an action potential
  • They open cation channels that hyperpolarize the cell membrane and decrease the likelihood of generating an action potential
  • They open anion channels that hyperpolarize the cell membrane and decrease the likelihood of generating an action potential
  • They open cation channels that depolarize the cell membrane and increase the likelihood of generating an action potential

Question 15

Question
117. Which one of the following statements is not true regarding chemical signaling between neurons?
Answer
  • Neurotransmitter synthesis may be stimulated by influx of Ca2+
  • NE-releasing neurons have presynaptic α receptors, which are involved in a negative feedback system to stop NE release
  • Once dopamine is released into the synaptic cleft it works until it diffuses away or is removed by reuptake mechanisms
  • Exocytosis is the process by which neurotransmitter storage vesicles release their contents into the synaptic cleft
  • Monoamine oxidase type B (MAO-B) metabolizes NE and serotonin

Question 16

Question
125. Which one of the following ions uses the second ion channel to open during an action potential, acts as a second messenger once in the neuron, activates the release of neurotransmitter, and activates ion channels that allow for influx of other ions that halt the action potential?
Answer
  • Na+
  • K+
  • Cl−
  • Ca2+
  • IP(3)

Question 17

Question
127. Which one of the following statements is true regarding inhibitory neurotransmitters?
Answer
  • They open chloride channels that depolarize the cell membrane and increase the likelihood of an action potential
  • They open cation channels that depolarize the cell membrane and increase the likelihood of an action potential
  • They open chloride channels that hyperpolarize the cell membrane and increase the likelihood of an action potential
  • They open chloride channels that hyperpolarize the cell membrane and decrease the likelihood of an action potential
  • They open potassium channels that depolarize the cell membrane and decrease the likelihood of an action potential

Question 18

Question
13. Which one of the following neurotransmitters works as an adjunctive neurotransmitter for glutamate as well as an independent neurotransmitter with its own receptors?
Answer
  • GABA
  • Norepinephrine
  • Serotonin
  • Dopamine
  • Glycine

Question 19

Question
29. Which one of the following neurotransmitters has large numbers of receptors in the spinal cord, is synthesized primarily from serine, and has been the subject of research involving negative symptom reduction in schizophrenia?
Answer
  • GABA
  • Glycine
  • Serotonin
  • Dopamine
  • Glutamate

Question 20

Question
69. Which one of the following brain structures’ dopaminergic neurons have been linked with Tourette’s syndrome and the development of tics?
Answer
  • Caudate
  • Substantia nigra
  • Amygdaloid body
  • Frontal cortex
  • Hippocampus

Question 21

Question
80. Alcohol, benzodiazepine sedative-hypnotic agents, and barbiturates all predominantly exert their clinical effects on the brain at which one of the following receptor sites?
Answer
  • Cholinergic nicotinic
  • NMDA
  • Glycine
  • GABA-A
  • GABA-B

Question 22

Question
81. An elderly man comes into his doctor’s office with symptoms of dementia and notable loss of executive functioning. Dysfunction of which one of the following brain regions would be most closely associated with the patient’s loss of executive functioning?
Answer
  • Caudate nucleus
  • Putamen
  • Globus pallidus
  • Frontal lobes
  • Temporal lobes

Question 23

Question
93. Which one of the following dopaminergic pathways or areas is associated with the antipsychotic effects of the antipsychotic medications?
Answer
  • Nigrostriatal pathway
  • Mesolimbic–mesocortical pathway
  • Tuberoinfundibular pathway
  • Caudate nucleus
  • Amygdaloid body

Question 24

Question
3. Which one of the following is true regarding norepinephrine (NE) and/or the locus ceruleus?
Answer
  • NE is synthesized in the locus ceruleus
  • Dopamine is synthesized in the locus ceruleus, NE in the dorsal raphe nuclei
  • Acetylcholine is synthesized with NE in the substantia nigra
  • γ-Aminobutyric acid (GABA) is synthesized in the locus ceruleus
  • The locus ceruleus is the site of formation of serotonin

Question 25

Question
25. The highest rate of synapse formation in the brain takes place during which one of the following time periods?
Answer
  • Adolescence
  • Weeks 32 to 35 of gestation
  • Weeks 13 to 26 of gestation
  • Within the first 6 weeks of gestation
  • As a toddler

Question 26

Question
41. Which one of the following receptor subtypes is associated with the neurotransmitter glutamate?
Answer
  • Nicotinic
  • Muscarinic
  • α1
  • α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)
  • GABA

Question 27

Question
71. Which one of the following is not true regarding the N-methyl-d-aspartate (NMDA) receptor?
Answer
  • The NMDA receptor has been linked with learning and memory
  • The NMDA receptor allows for the passage of potassium only
  • The NMDA receptor opens only when it has bound two molecules of glutamate and one molecule of glycine
  • The NMDA receptor can be blocked by physiological concentrations of magnesium
  • The NMDA receptor can be blocked by PCP

Question 28

Question
76. Emotional memory localizes to the:
Answer
  • Amygdala
  • Hippocampus
  • Primary auditory cortex
  • Nucleus basalis of Meynert
  • Pons

Question 29

Question
93. Which one of the following drugs is both an opioid agonist and antagonist?
Answer
  • Aripiprazole
  • Naltrexone
  • Buprenorphine
  • Methadone
  • Gabapentin

Question 30

Question
102. Which one of the following neurotransmitters localizes predominantly to the basal forebrain and is responsible for memory, attention, and executive functioning?
Answer
  • Serotonin
  • NE
  • GABA
  • Glycine
  • Acetylcholine

Question 31

Question
108. The GABA-A receptor (the most predominant GABA receptor) is which one of the following
Answer
  • A sodium channel
  • A chloride channel
  • A calcium channel
  • . A potassium channel
  • A magnesium channel

Question 32

Question
134. Which one of the following structures is most critical to the formation of memory?
Answer
  • Right frontal lobe
  • Right parietal lobe
  • Thalamus
  • Cerebellum
  • Hippocampus

Question 33

Question
144. Which one of the following answer choices is true regarding aggression?
Answer
  • High levels of cerebrospinal fluid (CSF) serotonin are associated with increased aggression
  • Serotonin is unrelated to aggression
  • Low levels of CSF serotonin are associated with increased aggression
  • Low levels of CSF serotonin are associated with decreased aggression
  • Low levels of dopamine are associated with increased aggression

Question 34

Question
Blocking the H1 receptor will lead to which of the following?
Answer
  • Weight gain
  • Dry mouth
  • Orthostatic hypotension
  • Elevated prolactin
  • Urinary retention

Question 35

Question
106. Which of the following neurochemical changes would you expect to see in a patient with increased aggression?
Answer
  • Increased serotonin
  • Decreased dopamine
  • Decreased testosterone
  • Decreased GABA
  • Decreased acetylcholine

Question 36

Question
43. Which of the following brain pathways starts in the ventral tegmental area and projects to the frontal cortex?
Answer
  • Tuberoinfundibular pathway
  • Nigrostriatal pathway
  • Mesolimbic pathway
  • Mesocortical pathway
  • Ventral amygdalofugal pathway
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