Melatonin

Description

Subcategory of Circadian Endocrinology
Woody Payne
Quiz by Woody Payne, updated more than 1 year ago
Woody Payne
Created by Woody Payne over 8 years ago
19
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Resource summary

Question 1

Question
Melatonin exerts its effects by:
Answer
  • Acting as an ultradian hormone.
  • Acting as an antioxidant.
  • Acting upon melatonin receptors.
  • Acting upon adrenergic receptors.
  • Acting to protect mitochondrial and nuclear DNA.

Question 2

Question
Melatonin is produced by which of the following pathways. Substances: 1.Serotonin 2.Melatonin 3.L-Tryptophan 4.N-Acetyl Serotonin 5.5-HTP Enzymes: A.tryptophan 5-hydroxylase B.acetylserotonin O-methyltransferase C.AANAT D.5-HTP decarboxylase
Answer
  • 1B4D2A3C5
  • 3A5D1C4B2
  • 3A1C5D4B2
  • 1B4D3C2A5

Question 3

Question
Bioavailability and Half-Life of Melatonin
Answer
  • 30-50% and 30-50 Minutes.
  • 40-60% and 20 to 30 Minutes.
  • 15-25% and 60 to 90 Minutes.
  • 60-80% and 90 to 120 Minutes.

Question 4

Question
Melatonin is regulated by Norepinephrine by which pathway: Substance: 1.Norepinephrine Enzyme: A.PKA B.AANAT Receptor: a.Beta Adrenergic
Answer
  • 1aBA
  • Ba1A
  • AB1a
  • 1aAB

Question 5

Question
Light of which of the following wavelength criteria will not inhibit melatonin
Answer
  • Under 530 nm.
  • Over 480 nm.
  • Over 530 nm.
  • Under 480 nm.

Question 6

Question
Dopamine plays a role in Melatonin secretion by:
Answer
  • Providing negative feedback to Melatonin formation.
  • Upregulating Melatonin receptors.
  • Enhancing the effects of Norepinephrine on Melatonin secretion.
  • Increasing in response to Melatonin binding with receptors.

Question 7

Question
5HT has which of the following functions and changes:
Answer
  • It decreases Serotonin production.
  • It is decreased by AANAT to be converted to Melatonin.
  • It is produced only during the day.
  • Its production leads to increased sympathetic activity and receptor activation on the pineal gland, ultimately leading to decreased Melatonin synthesis.
  • Dopamine activation of the D4 receptor heteromeres decreases 5HT in the morning.

Question 8

Question
The Pineal Gland is located outside of the blood brain barrier.
Answer
  • True
  • False

Question 9

Question
Melatonin affects the following hormones by:
Answer
  • Increasing LH.
  • Decreasing FSH.
  • Decreasing Leptin.
  • Increasing Prolactin and Cytokines.
  • Decreasing Corticosterone.
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