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Complimentation Tests & Epistasis
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Questions in this quiz (13)
1The complimentation test is used to find out if mutations are allelic or non allelic
- ATrue
- BFalse
2In what circumstances will a Complimentation Test give a false result?
- AWhen the mutation is recessive
- BWhen the mutation is dominant
- CWhen the mutated gene is part of a complex
- DWhere proteins form multimers
3Genotypes M1 & M2 are bred together, and a Wild Type result is obtained- are the mutations allelic
- ANo- as the presentation of a wild type phenotypes shows there is at least one dominant wild type allele for each gene
- BYes- The two mutations on the same allele are able to compliment each other sufficiently to produce a wild type phenotype
4If M3 and M2 are bred together and they present as M2, what does this tell us about the mutation's location?
- AThey are on the same allele- there is no dominant wild type allele to mask their activity
- BThey are on separate alleles, but M2 has a far greater effect than previously thought
5According to the above table, which mutations are allelic
- AM9 & M4
- BM8 & M6
- CM2
- DAll of the above
6A Complimentation Test can be fooled if the mutant protein can form a functioning heterodimer with the wild type protein
- ATrue
- BFalse
7One gene is said to be epistatic to another if...
- AThe presence of a double mutant exhibits the phenotype of the mutant gene
- BThe presence of the wild type masks the phenotype of the mutant gene
- CA genes expression causes a change in the expression of another gene further down the pathway
8Where are epistatic genes usually found in substrate dependent pathways?
- AUpstream
- BDownstream
9A substrate dependent pathway is a series of positive and negative regulators that act on one another of the final product
- ATrue
- BFalse
10This image is of a Switch Regulatory Pathway
- ATrue
- BFalse
11Why should null alleles be used for epistatic analysis (i.e how to find out the order of gene function in a pathway)
- AThe masking of alleles downstream becomes obvious
- BThey are easier to make than hypomorphic alleles
- CThey can be used for both Substrate Dependent and Switch pathways
12How do we identify that the pathway effected by the (epistatic) mutation is a Switch Regulatory pathway?
- AIf the mutation prevents the production of the final product
- BIf the phenotype of a double mutant is different to the phenotype of either single mutant
13The Rif1 & Rif2 strains are both causes lengthened telomeres, as shown in the diagram. Based on the Rif1/Rif2 double mutation, which of the two availible pathways (shown) is likely to be the one used?
- APathway A
- BPathway B
Information
- Description
- Year 2 Quiz on Complimentation Tests & Epistasis, created by gina_evans0312 on 16/12/2013.
- Author
- gina_evans0312
- Language
- English
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