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stem cells exam 2
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Questions in this quiz (43)
1vertebrates have similar developmental program
- Atrue
- Bfalse
2gastrulation is a phase early in the embryonic development of most animals, during which the single-layered blastula is reorganized into trilaminar ("three-layered") structure known as the gastrula. These three germ layers are called:
- Aectoderm
- Bmesenchyme
- Cendoderm
- Dmesoderm
- Eectochyme
3hox genes (from an abbreviation of homeobox) are a group of related genes that control the body plan of the embryo along the anterior-posterior (head-tail) axis.
- ATrue
- BFalse
4the segmental plate mesoderm is determined after somitogenesis
- ATrue
- BFalse
5the bilaterally symmetric body plan of vertebrates features several consistent asymmetries in the placement, structure, and function of organs such as the gut, heart and lungs
- ATrue
- BFalse
6the mesoderm of a neurula-stage embryo can be divided into three regions. the last region is the chordamesoderm
- ATrue
- BFalse
7which of the following are important for the conversion of the myoblasts into muscles in culture
- AWnt
- BShh
- CMyoD
- DMyf5
- Eall of the above
8endochondral ossification is the process by which the embryonic cartilaginous model of most bones contribution to longitudinal growth and is gradually replaced by bone.
- ATrue
- BFalse
9the first mouse ES cells were isolated in
- A1962
- B1981
- C1975
- D2006
- E2012
10pre-implantation embryos can be cryopreserved (frozen) for:
- A1-day
- B1-week
- C1-month
- D1-year
- Eindefinitely
- Fnone of the above
11who among the following did NOT receive the 2007 Nobel Prize:
- AMartin Evans
- BMario Capecchi
- CGail Martin
- DOliver Smithies
- Eall of the above
12Embryonic stem cells lines from Human blastocyst was first achieved in:
- A1962
- B1981
- C1987
- D1998
- E2006
- Fnone of the above
13Dr. James Thomson achieved scientific recognition among other things for:
- Afounding the Gurdon Institute in the UK
- Bmaking the first successful zebra-donkey hybrid - the zonkey
- Cisolating iPS cells from human somatic cells
- Dbeing the first to patent human IVF technology
- Enone of the above
14which of the following is NOT an aspect of "stem cell division and differentiation"
- Aprogenitor cell
- Bdifferentiated cell
- Csymmetric stem cell division
- Dprogenitor division
- Eterminal differentiation
- Fnone of the above
15which of the following is NOT a key definition of a stem cell
- Aa stem cell is not itself terminally differentiated or at the end of a differentiation pathway
- Ba stem cell can divide without limit
- Ca stem cell rapidly runs out of telomeres and stops dividing
- Dwhen a stem cell divides each daughter cell has a choice:
--it can remain a stem cell
--or it can embark on a course leading to differentiation - Enone of the above
16stem cell division and differentiation generally follows the path:
1. progenitor division
2. symmetric stem cell division
3. terminal differentiation
4. asymmetric stem cell division- A1-2-3-4
- B3-4-1-2
- C2-4-1-3
- D2-3-1-4
- E4-1-2-3
17which of the following is NOT a type of stem cell
- Atotipotent stem cells
- Bpluripotent stem cells
- Cmultipotent stem cells
- Dunipotent progenitor stem cells
- Einduced pluripotent stem cell
- Fnone of the above
18decreasing Oct4 protein concentration in an ES cell by 50% causes the ES cell to:
- Aself-renew
- Bdifferentiate into primitive endoderm
- Cdifferentiate into trophectoderm
- Ddifferentiate into primitive mesoderm
- Eall of the above
19a chimera is an animal that:
- Ahas been injected with DNA into the spermatocyte
- Bis composed of cells originating from two or more embryos
- Chas been injected with DNA into the oocyte
- Dhas an elongated life span
- Enone of the above
20primordial germ cells are sometimes referred to as:
- Athe first germ layer
- Bthe second germ layer
- Cthe third germ layer
- Dthe fourth germ layer
- Enone of the above
21Blimp1, Prdm14 and Stella play key roles in:
- Acirculation developmental
- Bmarrow development
- Cprimordial germ cell development
- Dneural tube closure
- Eall of the above
22signaling pathways responsible for the induction and maintenance of primordial germ cells primarily involve the Wnt family
- ATrue
- BFalse
23what is generally not permitted in humans
- Atherapeutic cloning
- Bcord blood banking
- Cbone marrow transplants between siblings
- Dreproductive cloning
- Ecryogenesis of IVF generated blastocysts
24in somatic cloning the term EF stands for
- Aearly fertilization
- Beasy fixation
- Celectrofusion
- Delongated fertilization
- Enone of the above
25telomere length is restored to physiological length at the:
- A2-cell to 4-cell transition
- B4-cell to 8-cell transition
- Cmorula to blastocyst transition
- Dall of the above
- Enone of the above
26ICNI stands for:
- AIntercystic nucleic acid inactivation
- BIntercytoplasmic nucleus injected
- CIntracytoplasmic nuclear injection
- DIntracystic nucleic acid inactivation
- Enone of the above
27how many successive generations of mouse clones have been achieved by ICNI
- A0
- B1
- C5
- D25
- E125
- Fnone of the above
28Hwang Woo-Suk in south korea in 2004-2006 made headlines for
- Apublishing the creation of human embryonic stem cells via nuclear transfer
- Bhaving the fabricated paper retracted by the journal science
- Cregenerating a mastodon using a surrogate female elephant as host
- Dboth the publishing the creation of human embryonic stem cells via nuclear transfer and having the fabricated paper retracted by the journal science
- Eall of the above
29what magical ingredient aided the generation of Human SCNT embryos and derivation of NT-ESCs in a famous 2013 report
- Aascorbic acid
- Bnicotine
- Cchlorophyll
- Dcaffeine
- Easparagine
- Fnone of the above
30the average human requires approximately _____ new hematopoietic cells each day
- A10^3
- B10^5
- C10^7
- D10^9
- E10^11
- Fnone of the above
31blood stem cells divide into two major paths:
- Amyeliod
- Bleukocyte
- Clymphiod
- Dmyeliod and lymphiod
- Emyeloid and leukocyte
- Fnone of the above
32blood is primarily composed of
- Aleukocytes
- BRBCs
- Cplatelets
- Dlymphocytes
- Eleukocytes RBCs platelets
- FRBCs platelets lymphocytes
33hematopoiesis occurs FIRST in the
- Abone marrow
- Bliver
- CAGM
- Dyolk sac
- Elymph nodes
- Fall of the above
- Gnone of the above
34developmental time windows for shifting sites of hematopoiesis shows that in adult the principal site of hematopoiesis is the
- Ayolk sac
- BAGM
- Cplacenta
- Dfetal liver
- Ebone marrow
35curiously the Nine-banded armadillo always gives birth to monozygotic quadruplets (clones)
- ATrue
- BFalse
36which of the following animals has NEVER been cloned in the laboratory and then survived to adulthood
- Acat
- Bdog
- Chorse
- Dhuman
- Emice
37hematopoiesis is defined as
- Athe study of the liver and its function
- Bthe study of desert reptiles and their reproduction
- Cthe formation of blood or of blood cells in the living body
- Dall of the above
- Enone of the above
38blood stem cells divide into two major paths
- Amyeloid and lymphoid
- Bmyeloid and luekocyte
- Clymphoid and monocyte
- Dmyelocyte and erythrocyte
- Enone of the above
39which of the following DOES NOT belong in the HSC Niche in the adult bone marrow
- AHSCs
- BKit ligand
- CBMP
- DOsteoblasts
- Enone of the above
40which of the following is NOT a player in Transcription Factor Antagonism in Lineage determine in hematopoiesis
- AGATA-1
- BEKLF
- CPU.1
- DOCT4
- EAll of the above
- Fnone of the above
41which one of the following statements is FALSE regrading leukocytes
- Asame as white blood cells
- Bare cells of the immune system involved in defending the body against both infectious disease and foreign materials
- Chave a plasma membrane but no nuclei or organelles and are packed with hemoglobin molecules
- Dlive for about three to four days in the average human
- Eare found throughout the body, including the blood and lymphatic system
42high quality or clinical grade human ES cells can be generated in apporximately
- A1 week
- B1 month
- C1 year
- D5 years
- Enone of the above
43chemicals can be used to enhance or replace core-reprogramming factors
- ATrue
- BFalse
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- Stem cells and regenerative medicine Quiz on stem cells exam 2, created by Ashley Flick on 18/10/2016.
- Author
- Ashley Flick
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- English
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