The main reason why rate of enzyme action increases with temperature initially is...
The kinetic energy of enzymes and substrates increases
Time passing, allowing more collisions to occur
The enzymes become denatured
More substrate is produced, therefore the enzymes become saturated
The level of a condition at which enzymes work best is called the [blank_start]optimum[blank_end] temperature/pH/etc.
Why do enzymes work less effectively in extreme pH, or in very high temperatures?
pH far from optimum affects bond interactions in the enzyme.
High temperatures provide enough kinetic energy to break bonds in the enzyme protein structure.
Enzymes become denatured.
Substrates have very high kinetic energy and collide too quickly with enzymes.
Enzyme tertiary structure changes.
The induced-fit hypothesis says that the active site tertiary structure remains constant when 'not occupied'.
The optimum temperature for enzymes in the human body is 37 degrees C.
Rate of reaction is proportional to..
The number of ESCs formed per second.
The number of enzyme proteins that become denatured by second.
The optimum temperature for a specific enzyme.
The solubility of ESCs formed in the reaction process.
There is a [blank_start]positive[blank_end] correlation between substrate concentration and initial rate of reaction. However, past a point, the graph [blank_start]plateaus[blank_end]. This is because of [blank_start]a limiting factor[blank_end], which is the [blank_start]enzyme concentration[blank_end]. At this point and beyond, the enzymes are said to be [blank_start]saturated[blank_end].
goes the opposite way
a limiting factor
enzyme's optimum temperature
space available in the cell
Cells create one set of enzymes that last for the duration of the cell's life.
Inhibitors that [blank_start]block[blank_end] the [blank_start]active site[blank_end] of enzymes are [blank_start]competitive[blank_end], whereas inhibitors that [blank_start]change[blank_end] the [blank_start]shape[blank_end] of enzymes are [blank_start]non-competitive[blank_end].
Which of the following statements are true about end product inhibition? Select all that apply.
Most metabolic reactions consist of one step.
An end product inhibits an enzyme that is responsible for its synthesis.
One product of the metabolic pathway inhibits the overall pathway.
The end product accumulates.
[blank_start]Potassium cyanide[blank_end] is an inhibitor that is also a metabolic poison. In the body, it forms [blank_start]hydrogen cyanide[blank_end]. The [blank_start]cyanide[blank_end] ions bind [blank_start]irreversibly[blank_end] to [blank_start]mitochondria[blank_end] and prevent normal [blank_start]aerobic respiration[blank_end].
Snake venom contains [blank_start]acetylcholinesterase[blank_end], which prevents the breakdown of [blank_start]acetylcholine[blank_end], thereby preventing muscle relaxation.
Various therapeutic drugs are available that work by inhibiting enzymes such as [blank_start]ACE[blank_end], [blank_start]proteases[blank_end], and [blank_start]ATPase[blank_end].