Quiz
Developmental biology
Questions in this quiz (43)
1Homozygous mutations of PAX6 in humans cause Aniridia
- ATrue
- BFalse
2what is at the vegetal pole of xenopus oocytes
- AVeg-1
- Byolk
- CMost mRNA's
- Dribosomes
- EtRNA's
3What is the cortical reaction?
- Aa block to polyspermy in the sea urchin
- BThe sperm penetrating through the egg membrane
- CActivation of the egg once sperm has enters
4What is the correct order of the life cycle of embryo development to adult
- Azygote->cleavage->gastrulation-> neurulation ->organogenesis->metamorphosis->adult
- Bzygote->cleavage->gastrulation-> organogenesis->neurulation->metamorphosis->adult
- Czygote->cleavage->gastrulation-> neurulation ->metamorphosis->organogenesis->adult
- Dzygote->cleavage-> neurulation->gastrulation ->organogenesis->metamorphosis->adult
5Which of the following apply the the PAX6 gene in drosophila
- APaired gene
- Bchromosome 11
- CGap gene
- Dchromosome 2
6Genes can change activity during development
- ATrue
- BFalse
7which of the following are cleavage patterns
- AHoloblastic
- BMeroblastic
- CSuperlateral
- DAll of these
8Sperm entry to the egg triggers Mg2+ release which acts on cell cycle proteins and initiates cleavage
- ATrue
- BFalse
9What does mesoderm give rise to?
- ACartilage
- BMuscle
- CBone
- DDermis
- EKidney
- FBlood
- GGut tissue
- Hepidermis
- INervous system
10What does ectoderm turn into
- AEpidermis
- BNervous system
- CGut tissue
- DBone
- ECartilage
- FMuscle
11C.elegans has no hedgehog signalling
- ATrue
- BFalse
12Which of these apply to the mutagenesis technique?
- ARandom gene is altered
- Bspecific gene is altered
- CMales treated with mutagen and crossed with wild-type females
- DFemales treated with mutagen and crossed with wild-type males
- Erecombinant DNA technology
13Which of these apply to the transgenesis technique?
- ARandom gene is altered
- Bspecific gene is altered
- Cgain of function of gene
- Dloss of function of gene
- Erecombinant DNA technology
14Which of these apply to the mutagenesis technique?
- ARandom gene is altered
- Bspecific gene is altered
- CMales treated with mutagen and crossed with wild-type females
- DFemales treated with mutagen and crossed with wild-type males
15Which organisms is mutagenesis a suitable gene
- AFly and zebrafish
- Bworm, Fly and zebrafish
- Czebrafish
- Dmouse, worm, Fly and zebrafish
16commitment is not shown by a fate map
- ATrue
- BFalse
17Regulative development is shown by models from the following scientists
- ADriesh- sea urchin
- BRoux- frog
- CBoth of these
18Which of the following applies to regulative development?
- Adamage to cells early on in development does not result in a defective organism
- Bdamage to cells early on in development results in a defective organism
- CCells determined early on
- Dnon-autonomous development
19most type of development is mosaic
- ATrue
- BFalse
20which of the following apply to the bicoid mRNA
- Ahighest concentration at posterior end
- BMaternal affect gene
- Ctranscription factor
- Dmutant larva lack thoracic segments
21The french flag model is a model for mosaic development
- ATrue
- BFalse
22Which experiment(s) is used to demonstrate competence?
- Axenopus cap assay
- BAmphibian organiser
- CBoth of these
23How many somites die in the C.elegans embryo
- Anone
- B5
- C72
- D131
- E896
24Which of the following are properties of an ideal marker?
- Anon toxic
- Bleaks so all cells have the marker
- CInherited by all progeny of the labelled cells
- Dvisible at later stages
25Which of the following are properties of an ideal marker?
- Anon toxic
- Bleaks so all cells have the marker
- CInherited by all progeny of the labelled cells
- Dvisible at later stages
26Which of the following are examples of markers
- Acytological markers
- Bvital dyes
- Chigh molecular weight tracers
- Dall of these
27MyoD is sufficient and required for muscle development
- ATrue
- BFalse
28Which term is this definition for? - over expression of transcription unit, it is a gain of function mutation
- Aamorph
- Bhypomorph
- Chypermorph
- DAntimorph
29In the Brachyury gene in the mouse, a homozygous mutation results in?
- Ashort tail
- Bembryonic lethal
30which organism(s) are unsuitable for mutagenesis and a mutagenesis screen
- Afrog and chick
- Bchick
- Cfrog, chick and bacteria
- Dfrog, chick and mouse
31Different mutations in the same gene is called and allelic series
- ATrue
- BFalse
32In complementation testing, if two genes complement each other they ...
- Aare alleles of the same gene, so lie in the same chromosome
- Bdo not lie in the same chromosome
33what are epistasis experiments used for?
- Aworking out the order of gene action in a pathway
- Bworking out which genes are in a pathway
- Cworking out if mutations are on the same or different genes
- Dworking out the genotype of a mutant
34The drosophila gene 'white' is required for the development of white eyes
- ATrue
- BFalse
35which of the following are defects from kit and steel mutations?
- AAnaemia
- Bcoat pigmentation
- Cembryonic lethal
- Dshort tail
36There are two classes of segment polarity genes; hedgehog-like and patched-like. Which genes belong to the hedge-hog like?
- AHh
- BSmo
- CWg
- Dall of these
37The body plan along the embryo is controlled by Hox genes along the DV axis
- ATrue
- BFalse
38which of the following maternal effect gene(s) are in the ventralised class?
- ADorsal
- BSpatzle
- CToll
- Dcactus
39what does local application of FGF4 after removal of AER results in..
- Ano effect
- Blimb development- radius and ulna fully developed but only partial digit development
- Climb development- but only partial development
- Dlimb development- Digits fully developed but radius and ulna only partially developed
40Length of time spent in AER determines cell fate according to position over proximal distal axis.
- ATrue
- BFalse
41In proneural clusters, one cells becomes a neuroblast (primary fate), whilst the other cells become the secondary fate which is..
- Aepidemermis
- Bneurons
- Cfibroblasts
- Dmesenchyme
42The proneural cluster gives rise to a neuroblast through lateral inhibition of which receptor and ligand pair?
- AKit and steel
- BDelta and Notch
- CFGF and FGFR
- DDelta and steel
43Most forms of Anchondroplasia come from mutations in which FGF gene?
- AFGF2
- BFGF3
- CFGF4
- DFGF5
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- questions covering all lectures
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- emmabrudenell
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