Developmental Lecture 8 onwards

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tmattimoe
Quiz by tmattimoe, updated more than 1 year ago
tmattimoe
Created by tmattimoe about 11 years ago
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Question 1

Question
A morphogen:
Answer
  • Is not expressed from a localised source in the embryo
  • Does not form a concentration gradient
  • Is not a signalling molecule
  • Specifies cell fates according to its concentration

Question 2

Question
Bicoid mRNA is tightly localised to the posterior end of the egg.
Answer
  • True
  • False

Question 3

Question
Which of the following is not an example of induction?
Answer
  • Xenopus animal cap assay
  • Homologous recombination
  • Anchor cell signalling to vulval precursors in the C.elegans embryo

Question 4

Question
In mosaic development, isolated cells are able to develop without external signalling.
Answer
  • True
  • False

Question 5

Question
Somites give rise to which of the following...? (Multiple answers)
Answer
  • Neural tube
  • Skeletal muscle
  • Notocord
  • Dermis
  • Glia

Question 6

Question
MyoD is sufficient to direct muscle development when transfected into non-muscle cells
Answer
  • True
  • False

Question 7

Question
Reverse genetics uses the mutant phenotype as a starting point
Answer
  • True
  • False

Question 8

Question
Which of the following are gain of function mutations...?
Answer
  • Amorph
  • Antimorph
  • Neomorph
  • Hypomorph
  • Hypermorph

Question 9

Question
Kit and Steel are in the same gene
Answer
  • True
  • False

Question 10

Question
Which of the following is the ligand-receptor pair Kit and Steel responsible for the normal development of...? (Multiple answers)
Answer
  • Melanoblasts
  • Keratinocytes
  • Germ cells
  • Fibrocytes
  • Megakaryocytes
  • Haematopoietic stem cells

Question 11

Question
Which one of the following is the correct Hh pathway sequence?
Answer
  • Hh ---| Ptc ---| Smo --> Ci ---> wg
  • Hh ---| Smo --> Ptc --> Ci ---| wg
  • wg ---> Ci ---> Ptc ---| Smo ---| Hh
  • wg ---| Smo ---| Ptc ---> Ci ---> Hh

Question 12

Question
Barchyury codes for a transcription factor responsible for the development of which germ layer?
Answer
  • Mesoderm
  • Ectoderm
  • Endoderm
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