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968070
Developmental Lecture 8 onwards
Description
(not finished)
Quiz by
tmattimoe
, updated more than 1 year ago
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Created by
tmattimoe
almost 10 years ago
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Resource summary
Question 1
Question
A morphogen:
Answer
Is not expressed from a localised source in the embryo
Does not form a concentration gradient
Is not a signalling molecule
Specifies cell fates according to its concentration
Question 2
Question
Bicoid mRNA is tightly localised to the posterior end of the egg.
Answer
True
False
Question 3
Question
Which of the following is not an example of induction?
Answer
Xenopus animal cap assay
Homologous recombination
Anchor cell signalling to vulval precursors in the C.elegans embryo
Question 4
Question
In mosaic development, isolated cells are able to develop without external signalling.
Answer
True
False
Question 5
Question
Somites give rise to which of the following...? (Multiple answers)
Answer
Neural tube
Skeletal muscle
Notocord
Dermis
Glia
Question 6
Question
MyoD is sufficient to direct muscle development when transfected into non-muscle cells
Answer
True
False
Question 7
Question
Reverse genetics uses the mutant phenotype as a starting point
Answer
True
False
Question 8
Question
Which of the following are gain of function mutations...?
Answer
Amorph
Antimorph
Neomorph
Hypomorph
Hypermorph
Question 9
Question
Kit and Steel are in the same gene
Answer
True
False
Question 10
Question
Which of the following is the ligand-receptor pair Kit and Steel responsible for the normal development of...? (Multiple answers)
Answer
Melanoblasts
Keratinocytes
Germ cells
Fibrocytes
Megakaryocytes
Haematopoietic stem cells
Question 11
Question
Which one of the following is the correct Hh pathway sequence?
Answer
Hh ---| Ptc ---| Smo --> Ci ---> wg
Hh ---| Smo --> Ptc --> Ci ---| wg
wg ---> Ci ---> Ptc ---| Smo ---| Hh
wg ---| Smo ---| Ptc ---> Ci ---> Hh
Question 12
Question
Barchyury codes for a transcription factor responsible for the development of which germ layer?
Answer
Mesoderm
Ectoderm
Endoderm
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