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Karteikarten

Connective tissue

Teresa Richards Veterinary bioscience - Cells to systems Englisch 25 Karten

Karten in diesem Stapel (25)

  1. 1What is the importance of histology- helps to understand normal function
    - provides basis for understanding of pathology
  2. 2What are the 5 stages of examination of tissues and briefly explain each stage1 - fixation - tissues fixed in formalin
    2 - embedding - paraffin wax
    3 - sectioning - microtome cuts 5um thick
    4 - staining
    5 - mounting
  3. 3Give 2 problems associated with histology1 - 2D representation of 3D structure - may not be representative of tissue
    2 - artefacts - PM change, air bubbles, variation in staining, folding, shrinkage, processing during sectioning
  4. 4Which areas of the cell typically stain blue and whyDNA in nucleus and RNA in ribosomes
    as they are actively synthesising protein
  5. 5Complete the following sentence Blast cell types are ____ differentiated, whereas cyte cell types are _____ differentiatednot fully
    fully
  6. 6Name the 4 basic tissue types1 - connective
    2 - epithelial
    3 - muscular
    4 - nervous
  7. 7Give the 6 classifications of connective tissue1 - embryonic connective tissue
    2 - connective tissue proper
    3 - cartilage
    4 - bone
    5 - blood and lymph
    6 - haemopoietic tissue
  8. 8What is the composition of connective tissue- cells and extracellular material
  9. 9What are the compositions of extracellular material- amorphous or fibrous
  10. 10Give 3 examples of amorphous extracellular material- fluid - blood, lymph
    - jelly like - humour
    - solid - bone, cartilage
  11. 11Give the 3 forms of fibrous extracellular material1 - collagen
    2 - reticular
    3 - elastic
  12. 12Describe the characteristics of collagen- strong and flexible
    - white fibrous tissue
    - eosinophilic in H&E
    - mostly type I collagen but can vary in specialised tissue
    - random arrangement
  13. 13Describe the characteristics of reticular fibres- fine network
    - poorly stained in H&E
    - RETICULIN STAIN - stains black
    - composed of varying combinations of collagen and ECM glycoprotein
    - not as strong as collagen - found where there is req to hold tissue together
  14. 14What are the characteristics of elastic fibres- stretchable, elastic
    - yellow, fibrous tissue
    - eosinophilic in H&E
    - VERHOEFFS STAIN - stains black
  15. 15Give 5 functions of connective tissue proper1 - support
    2 - protection
    3 - connections in locomotor system
    4 - holds tissue together
    5 - energy storage
  16. 16What are the 3 types of connective tissue proper1 - loose - higher ratio of cells to fibres
    2 - adipose - many fat cells
    3 - dense - lower ratio of cells to fibres
  17. 17Give the 8 cell types that can be found in connective tissue proper1 - mesenchymal
    2 - fibroblast
    3 - fibrocyte
    4 - macrophage
    5 - adipocyte
    6 - mast cell
    7 - plasma cell
    8 - melanocyte
  18. 18Give the appearance and location of a mesenchymal cell- appearance - stellate
    - many cytoplasmic process
    - oval, round nucleus
    - location - embryonic tissue
  19. 19Give the appearance and function of a fibroblast- appearance - stellate or spindle shaped
    - ovoid nucleus
    - abundant basophilic cytoplasm
    - synthesises and secretes collagen and ECM components
    - differentiates into fibrocyte
  20. 20Give the appearance of a fibrocyte- small flattened elongated cell
    - elongated nucleus
    - very little cytoplasm
    - less active in secretion that fibroblasts
  21. 21What is the function of a macrophage- derived from blood monocyte
    - phagocytic cell
    - produces lysosomal proteases, cytokines, prostaglandins
    -mediates inflammatory process
  22. 22What is the appearance and function of an adipocyte- accumulate fat droplets in cytoplasm
    - droplets coalesce to form single large fat droplet - displace nucleus to side of cell
    - energy storage, insulation and protection
  23. 23What is the appearance of a mast cell- scattered
    - low numbers in conn tissue
    - often close to blood vessels
    - cytoplasm filled with granules containing heparin, histamine, serotonin and proteases
    - degranulate when tissue damaged
  24. 24What is the appearance and function of a plasma cell- appearance - abundant basophilic cytoplasm
    - negative image (Golgi apparatus) prominent
    - eccentrically placed round nucleus
    - chromatin radially arranged
    - function - B lymphocyte actively producing antibody
  25. 25What is a melanocytepigment cell

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Veterinary bioscience - Cells to systems Karteikarten am Connective tissue, erstellt von Teresa Richards am 27/02/2018.
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Teresa Richards
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