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BRS Renal and Acid-Base Physiology

tiwariashley Physiology Lecture Lecture Englisch 33 Karten

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  1. 1Secretion of K+ by the distal tubule will be decreased byspironolactone administration
  2. 2Subjects A and B are 70kg men. Subject A drinks 2 L of distilled water and subject B drinks 2 L of isotonic NaCl. As a result of these ingestions subject B will have ahigher urine osmolarity
  3. 3A woman with a history of severe diarrhea has the following arterial blood values: pH: 7.25 PCo2: 24 mmHg HCo3-: 10 mEg/l venous blood samples show decreased blood K+ and a normal anion gap. the correct diagnosis for this patient ismetabolic acidosis
  4. 4A woman with a history of severe diarrhea has the following arterial blood values: pH: 7.25 PCo2: 24 mmHg HCo3-: 10 mEg/l venous blood samples show decreased blood K+ and a normal anion gap. The decreased blood K+ is a result ofincreased circulating levels of aldosterone
  5. 5The reabsorption of filtered HCO3-is inhibited by decreases in arterial PCO2
  6. 6To maintain normal H+ balance total daily excretion of H+ should equal the dailyfixed acid production plus fixed acid ingestion
  7. 7One gram of Mannitol was injected into a woman. After equilibrium a plasma sample had a mannitol concentration of .8g/l. During the equilibrium period 20% of the injected mannitol was excreted in the urine. The subjectsECF volume is 10L
  8. 8At plasma concentrations of glucose higher than occur at transport maximum theexcretion of glucose increases with the increasing plasma glucose concentration
  9. 9a negative free-water clearance(-CH20) will occur in a person whohas an oat cell carcinoma of the lung and excretes urine with an osmolarity of 1000 mOsm/L
  10. 10A buffer pair(HA/A-) has a pK of 5.4. at a blood pH of 7.4 the concentration of HA is1/100 that of A-
  11. 11What would produce and increase in the reabsorption of isosmotic fluid in the proximal tubuleincreased filtration fraction
  12. 12Which two substances can be used to measure interstitial fluid volumeinsulin and radioactive albumin
  13. 13At plasma para-aminohippuric acid ( PAH) concentrations below the transport maximum PAHconcentration in the renal vein is close to zero
  14. 14Compared with a person who ingests 2 L of distilled water a person with deprivation will have ahigher rate of H2O reabsorption in the collecting ducts
  15. 15What would cause an increase in both the glomerular filtration rate (GFR) and renal plasma flow (RPF)dilation of the afferent arteriole
  16. 16Which of the following would best distinguish an otherwise healthy person with seven water deprivation from a person with the syndrome of inappropriate antidiuretic hormone (SIADH)plasma osmolarity
  17. 17What causes a decrease in renal Ca2+ clearancetreatment with chlorothiazide
  18. 18A patient has the following arterial blood values: pH: 7.52 PCO2: 20 mm Hg HCO3: 16 mEq/l Which statements about the patient is correcthe has decreased ionized Ca2+ in blood
  19. 19A patient arrives at the ER with low arterial pressure, reduced tissue turgor and the following arterial blood values: pH= 7/69 HCO3= 57mEq/L PCO2= 48 mm Hg What response would be expected to occur in this patientexchange of intracellular H+ for extracellular K+
  20. 20which ion has a higher concentration in intracellular fluid then in extracellular fluidK+
  21. 21a woman has a plasma osmolarity of 300 mOsm/l and a urine osmolarity of 1200 mOsm/L the correct diagnosis iscentral diabetes insipidus
  22. 22A patient is infused with para-aminohipuric acid (PAH) to measure renal blood flow (RBF). She has a urine flow rate of 1ml/min a plasma PAH of 1mh/ml a urine PAH of 600 mh/ml and hematocrit of 45%. What is her effective RBF1091 ml/min
  23. 23What substance has the highest renal clearancePAH Para-aminohippuric acid
  24. 24A woman runs a marathon in 90 degree weather ad replaces all volume lost in sweat by drinking distilled water. After the marathon she will havedecreased plasma osmolarity
  25. 25what causes hyperkalemiaexercise
  26. 26What is the cause of metabolic alkalosishyperaldosteronism
  27. 27What does the parathyroid hormone do on the renal tubulestimulate adenylate cyclase
  28. 28A man presents with hypertension and hypokalemia. Measurement of his arterial blood pressure reveals a pH of 7.5 and a calculated HCO3- of 32 mEq/L. His serum cortisol and urinary vanillylmandelic acid VMA are normal his serum aldosterone is increased. and his plasma renin activity is decreased. What is the cause for his hypertensionConn's Syndrome
  29. 29What set of arterial blood values describes a heavy smoker with a history of emphysema and chronic bronchitis who is becoming increasingly somnolentPh 7.32
    HCO3- 30
    PCO2 60
  30. 30What set of arterial blood values describes a patient with partially compensated respiratory alkalosis after 1 month on a mechanical ventilatorPh 7.50
    HCO3- 15
    PCO2 20
  31. 31What set of arterial blood values describes a patient with chronic renal failure ( eating a normal protein diet) and decreased urinary excretion of NH4Ph 7.31
    HCO3- 16
    PCO2 33
  32. 32What set of arterial blood values describes a patient with untreated diabetes mellitus and increased d urinary excretion of NH4Ph 7.31
    HCO3- 16
    PCO2 33
  33. 33What set of arterial blood values describes a patient with a 5 day history of vomitingPh 7.65
    HCO3- 48
    PCO2 45

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Physiology at UCF
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