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Karteikarten

Cell Line Traits

gina_evans0312 Year 2 Englisch 19 Karten

Karten in diesem Stapel (19)

  1. 1Primary/Immortal Cells - Anchorage DependentYes
  2. 2Primary/Immortal Cells - Growth Factor DependentYes
  3. 3Primary/Immortal Cells - Density Dependent InhibitionYes
  4. 4Primary/Immortal Cells - MorphologyFlat, extended growing surface with elongated stress fiber network
  5. 5Primary/Immortal Cells - Monolayer GrowthYes
  6. 6Density Dependent InhibitionCells will stop dividing once in full contact with other cells- forming a monolayer
  7. 7Growth FactorsAllow signaled proliferation only (found in serum) in normal cells
  8. 8Transformed Cell LineImmortalised cell line that could form tumors in the immunocompromised
  9. 9Transformed Cell Line - Anchorage DependentNo
  10. 10Transformed Cell Line - Responds to Apoptic SignalsNo
  11. 11Transformed Cell Line - Growth Factor DependentReduced, but not gone- autocrine stimulation
  12. 12Autocrine StimulationCell produces chemicals that signal itself
  13. 13Transformed Cell Line - Density Dependent InhibitionNo- leads to necrosis of cells below surface
  14. 14Transformed Cell Line - Increased Metabolic RateYes- inc. Glucose transport, lactate production & protein generation
  15. 15Warburg EffectCells metabolise differently- glycolysis & lactic acid fermentation, which is detectable
  16. 16Transformed Cell Line - MorphologyNo defined shape, increased motility, decreased surface fibrinogen
  17. 17FibrinogenProtein that attaches cells to each other & causes density dependent inhibition
  18. 18Tumerogenic CellIf injected into healthy mice, these cells will invade & metastasie tissue
  19. 19E-CadherinAlso prevents density dependent growth

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Beschreibung
Year 2 Karteikarten am Cell Line Traits, erstellt von gina_evans0312 am 01/12/2013.
Erstellt von
gina_evans0312
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