4331832
Quiz by Joe Wanford, updated more than 1 year ago
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Created by Joe Wanford
about 5 years ago
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Description
Question 1
Question
Mutations are a change in an organisms [blank_start]DNA[blank_end]. DNA mutations can result in a change in protein structure or not, these are referred to as non-[blank_start]synonymous[blank_end] and [blank_start]synonymous[blank_end] mutations respectively. Mutations can involve the [blank_start]substitution[blank_end] of one base for another, or the [blank_start]deletion[blank_end]/[blank_start]insertion[blank_end] of a base.
Answer
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DNA
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synonymous
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synonymous
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substitution
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deletion
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insertion
Question 2
Question
The reading frame of a piece of DNA determines which [blank_start]amino[blank_end] acids are assembled into a [blank_start]protein[blank_end] molecule. Insertions and deletions can cause [blank_start]frame[blank_end] shifts, [blank_start]changing[blank_end] the codons downstream of the mutation.
Answer
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amino
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protein
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frame
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changing
Question 3
Question
Mutations are responsible for over 4000 [blank_start]genetic[blank_end] diseases in humans. Some of these diseases stem from just a single [blank_start]nucleotide[blank_end] mutation. One example of this is in cystic [blank_start]fibrosis[blank_end], which is caused by mutation of the gene encoding the CFTR protein. One of the most well known genetic diseases worldwide is [blank_start]cancer[blank_end].
Answer
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genetic
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nucleotide
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fibrosis
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cancer
Question 4
Question
Cancer is caused by cells losing their ability to control cell [blank_start]division[blank_end], to undergo programmed cell [blank_start]death[blank_end] and many other hallmarks. Cancer progression occurs following a sequence of [blank_start]mutations[blank_end] in [blank_start]tumour[blank_end] [blank_start]suppressor[blank_end] [blank_start]genes[blank_end] and proto-[blank_start]oncogenes[blank_end].
Answer
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division
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death
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mutations
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tumour
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suppressor
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genes
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oncogenes
Question 5
Answer
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Cancerous cell
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Healthy cell
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Mutations in oncogenes
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Mutations in TSGs
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Mutations in oncogenes and TSGs
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Healthy growth
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Malignant cells
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Healthy cells
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Cells with a single mutation
Question 6
Question
The likely hood of cancer is increased if you are exposed to [blank_start]mutagens[blank_end]. This is because mutagens increase the [blank_start]mutation[blank_end] [blank_start]rate[blank_end] of your cells.
Answer
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mutagens
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mutation
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rate