Vaccinations

Vaccinations

1. advers reactions

   • injection site fibrosarcoma (FeLV and rabis vac in cats)
     • thought to be caused by the adjuvient within the vaccine cause genetic changes predisposing to neoplasie (Day,2006)
     • occurs in 1-4% of 10,000 cats vacc with FeLv
     • RSPCA recommends only vaccinating cats that are at risk however this is most cats
     • appear 3 months to four years after vaccination
     • surgical treatment is requied and if cells are left behind is likely to return
   • anaphalaxsis
     • foestal cafl serum used as a media for the virus seems to be the causative facotr
     • the use of antihistimines before a vaccination is given when it is madatory is recommended
     • dogs- excitement, U+,D+,V+, followed by collapse, depression coma convulsions and death Cats- histiman release causes facial swallling, pawing at face, dysponea, salvation, vomiting, collapse and death
   • non-spacific reaction
     • fever swollen lymphglands usually resolves it self withing 7 days a sign that the vaccine worked thoug may effect owner opinion of vaccine
   • auto-immun disease
     • auto immun heamalytic anneam
       • linked to parvo
       • modified live multipal angigen vaccines
       • tringgers antibody production that lables RBC for deistruction
       • anorxia, exercise intolerence, increased HR, difficulty breathing, V and D
       • can be life threathing and requires fluids and steriods
     • hypertrophic osteodysthrophy
       • combined vaccines seems to increase the risk
       • decreases blood flow in metaphyses leading to failur to ossify leading to necrosis and inflammation of the bone
       • weimaraner puppies most affected
       • occurs 10 days after vaccince, anorexia, depression, gi and resp problems, angular limbs

2. vacination protocols

   • cat
     • calicivirus, hepititis and leukemia every year
     • enteritis every 3 years though some recommend every year
   • dogs
     • DHP every three years
     • lepto and parainfluenza every year
     • kc every year if given
   • rabies every 3 years

3. known problems

   • MDAs
   • breed predisposing factors such as black and tan and pparvo
   • inproper storage
   • inproper administration
   • aniamls are individuals
     • titre level monitoring is available