Zusammenfassung der Ressource
GnRH Mechanism
- Desensitization
- Slow Rise rate looks like
continous stimulation
- Effect on FSH release
- Stimulatary patterns did not change the release of LH/FSH
- Due to desensitization to GnRH pulses
- Ratio of FSH:GnRH due to
- Differential Clearance
- Ovarian Feedback
- Differential Synthesis in intact tissue
- Other hormones that cause FSH secretion
- Steroid Feedback Mechanism
- Castrated
- Males
- Effects Testosterone that
decreases frequency and
amplitude
- Females
- Increases GnRH receptors but
blocked if estrogen or other
steroids are given
- Stimulatory Signals
- Pulse
Amplitude
- Interval
- Duration
- Rise Rate
- Graph Shows
- For effective reponse
- Pulse
- Wide Spread
- Short
- A large about of LH released when GnRH added