Frage 1
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What is the filtration barrier formed by?
Frage 2
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What is the basement membrane of the filtration barrier formed by?
Frage 3
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What does the basement membrane of the filtration barrier provide?
Antworten
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a charge barrier
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a source of energy
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a microphalange
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urine
Frage 4
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What type of function does the basement membrane of the filtration barrier have?
Antworten
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a sieving function
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a saving function
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a blocking function
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a stimulating function
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a reduction function
Frage 5
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Determinants of glomerular filtration.
[blank_start]Jv[blank_end] = [blank_start]k[blank_end] x [blank_start]S[blank_end]( Δ [blank_start]P[blank_end] - Δ [blank_start]Π[blank_end] )
Frage 6
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In the determinants of glomerular filtration formula, Jv =
Antworten
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flux
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hydraulic conductivity
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hydraulic pressure
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surface area
Frage 7
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In the determinants of glomerular filtration formula, k =
Antworten
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flux
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hydraulic conductivity
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hydraulic pressure
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surface area
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gradient
Frage 8
Frage
In the determinants of glomerular filtration formula, S =
Antworten
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surface area
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flux
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oncotic pressure
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gradient
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hydraulic pressure
Frage 9
Frage
In the determinants of glomerular filtration formula, P =
Antworten
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hydraulic pressure
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oncotic pressure
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hydraulic conductivity
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flux
Frage 10
Frage
In the determinants of glomerular filtration formula, Π =
Antworten
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oncotic pressure
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flux
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hydraulic pressure
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surface area
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hydraulic conductivity
Frage 11
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Hydraulic conductivity is defined as the [blank_start]flux[blank_end] of [blank_start]water[blank_end] ([blank_start]and small solutes[blank_end]) per unit [blank_start]time[blank_end] for a defined [blank_start]pressure[blank_end] gradient and [blank_start]surface[blank_end] area.
Antworten
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flux
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water
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and small solutes
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time
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pressure
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surface
Frage 12
Frage
The hydraulic conductivity of the glomerular capillary wall is _________ fold higher than other capillaries.
Antworten
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40 - 50
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90-100
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10-20
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5-6
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20-25
Frage 13
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Glomerular capillaries work at _____ pressures than other capillaries
Frage 14
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Hydrostatic pressure in glomerular capillaries is relatively _________
Frage 15
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Colloid oncotic pressure ________ in the glomerular capillaries
Antworten
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increases
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decreases
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stays constant
Frage 16
Frage
label the pressures
Frage 17
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What controls Glomerular Capillary Pressure?
Frage 18
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What controls resistances of afferent arteriole and efferent arteriole?
Antworten
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neural and hormonal inputs
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glomerular capillary pressure
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blood flow
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vaso constriction and dilation
Frage 19
Frage
What affect does changes in resistance of the afferent arteriole and efferent arteriole have?
Antworten
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lower than if equal resistances
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higher than if equal resistances
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equal to if equal resistances
Frage 20
Frage
Why is it so important to control and maintain the Glomerular Capillary Pressure constant?
Antworten
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to ensure GFR is constant
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to avoid excess unnecessary urine being made
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to avoid pain
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to maintain an equal level of hormones
Frage 21
Frage
Which graph relates to afferent arteriole constriction and which relates to efferent arteriole constriction?
Frage 22
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A 25% increase in mean arterial blood pressure will cause a ____% increase in GFR and a loss of __L per day.
Antworten
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25%, 40L
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50%, 80L
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75%, 100L
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2.5%, 4L
Frage 23
Frage
What are the 3 important mechanisms in regulating GFR?
Frage 24
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The movement of any molecule across the filtration membrane is measured by its [blank_start]flux[blank_end]
Antworten
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flux
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hydraulic conductivity
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speed
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molecular weight
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oncotic pressure
Frage 25
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Hydraulic conductivity is very _____ in glomerular capillaries
Antworten
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high
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low
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changeable
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constant
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annoying
Frage 26
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Hydrostatic pressure gradient is the gradient acting ....
Antworten
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between the inside and outside of the capillary and bowmans space.
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between the glomerulus and afferent arteriole
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between the efferent and afferent arteriole
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between the inside and outside of the capillary
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between the inside and outside of bowmans space.
Frage 27
Frage
Kf in relation to GFR is...
Antworten
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ultrafiltration coefficient
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net ultrafiltration pressure
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net friction along capillary walls
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hydrostatic pressure.
Frage 28
Antworten
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other
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glomerular
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capillary hydrostatic pressure
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filtration pressure equilibrium
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capillary colloid osmotic pressure
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glomerular capillaries
Frage 29
Antworten
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glomerular capillary hydrostatic pressure
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Bowman’s space oncotic pressure
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Bowman’s space hydrostatic pressure
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glomerular capillary oncotic pressure
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efferent arteriole
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afferent arteriole
Frage 30
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There is net filtration along the entire length of the glomerular capillaries
Frage 31
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Net filtration pressure = [blank_start]glomerular capillary pressure[blank_end] - ( [blank_start]colloid oncotic pressure[blank_end] + [blank_start]Bowman’s space pressure[blank_end] )
Frage 32
Frage
Label grr regulation graph
Frage 33
Antworten
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renal corpuscle
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renal sympathetic nerve
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afferent arteriole
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juxtaglomerular cells
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macula densa
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efferent arteriole
Frage 34
Frage
Granular juxtamedullary cells are...
Antworten
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Located in afferent arteriole
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Store and secrete renin
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Their effects result in angiotensin 2 formation
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Decrease sodium absorption
Frage 35
Frage
The granular juxtamedullary cells ...
Antworten
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Directly increase total PR
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Directly increase systemic blood pressure
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Indirectly increase sodium reabsorption
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Indirectly increase potassium secretion
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Indirectly increase ECF volume
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Secrete ADH
Frage 36
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Auto-regulation of GFR ... [blank_start]increased stretch in afferent[blank_end] —-> [blank_start]afferent contraction[blank_end] —> [blank_start]decreased pressure [blank_end]—> [blank_start]no change in GFR[blank_end]
Frage 37
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Fill in flow chart...
Frage 38
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The macula densa senses fluid flow in the tubule
Frage 39
Frage 40
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Alport's syndrome is ...
Antworten
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hereditary glomerulonephritis
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due to mutations in the collagen chains of the glomerular basement membrane
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a pathological condition
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an inability to process proteins
Frage 41
Frage
Which of these are protein elements that can be found in the glomerular basement membrane?
Frage 42
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Which of these are true about the endothelial cell surface layer?
Antworten
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aka ESL
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seems to be a rather thick negatively charged structure
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most likely contributes to the high permselectivity of the glomerular wall
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is found on the luminal side of blood vessel walls
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it is never found in venules
Frage 43
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Small molecular weight neutral solutes have concentrations in the filtrate equal to those in plasma, this means they are freely filtered.