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Quiz von Med Student , aktualisiert more than 1 year ago
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Erstellt von Med Student
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Frage 1
Frage
Antifungals are:
Antworten
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tetracyclines
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imidazoles
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echinocandims
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triazols
Frage 2
Frage
Synthetic antifungal drugs are
Antworten
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Nystatin
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Itraconazole
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Ketoconazole
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Fluconazole
Frage 3
Frage
Antifungal antibiotics are:
Antworten
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Nystatin
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Tetracycline
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Gentamycin
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Amphotericin B
Frage 4
Frage
Azoles:
Antworten
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are fungistatic
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inhibit cell wall synthesis
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inhibit ergosterol synthesis
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inhibit hepatic CYP450 enzymes
Frage 5
Frage
lmidazoles are:
Antworten
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Fluconazole and ltraconazole
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Miconazole and Econazole
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Given topically
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Given systematically
Frage 6
Frage
Ketoconazole is:
Antworten
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the only imidazole that can be given orally
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used for treatment of bacterial skin infections
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used topically for cutaneous fungal infections
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used intravenously for treatment of systemic fungal infections
Frage 7
Frage
Fluconazole:
Antworten
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it is non- steroidal anti-inflammatory drug
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is triazole antifungal drug
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is administered orally or intravenously
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is excreted mainly unchanged with the urine
Frage 8
Frage
ADRs of azole antifungals are:
Antworten
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hepatotoxicity
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endocrine disorders
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nephrotoxicity
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nausea, vomiting
Frage 9
Frage
Point the correct statements for Nystatin:
Antworten
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has fungistatic activity
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causes gastrointestinal disturbances
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is effective against Trichomonas vaginalis
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is effective against Candida species
Frage 10
Frage
ADRs of Amphoteracin B are:
Antworten
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renal impairment
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hypokalemia
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hypotension
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liver impairment
Frage 11
Frage
Antiviral drugs act by following mechanisms
Antworten
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inhibition of viral “uncoating”
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inhibition of viral DNA or RNA synthesis
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inhibition of viral proteases
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inhibition of viral penetration into the cell
Frage 12
Frage
Point out the correct statements for Aciclovir:
Antworten
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it inhibits viral DNA polymerase
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it is used for “treatment of herpesvirus infections
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it inhibits neuraminidase enzyme
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can be applied topically, orally or intravenously
Frage 13
Frage
ADRs of Aciclovir are:
Antworten
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hepatotoxicity
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renal impairment
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local irritation
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encephalopathy (at high i.v. doses)
Frage 14
Frage
Drugs for prevention and treatment of flu are:
Antworten
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Aciclovir (Zovirax)
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Amantadin (Symmetrel)
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Rimantadin (Flumadine)
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Oseltamivir (Tamiflu)
Frage 15
Frage
Mechanism of action of Oseltamivir (Tamiflu) is
Antworten
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interference with the function of the viral M2 protein
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inhibition of specific neuraminidase enzyme
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inhibition of reverse transcriptases
-
inhibition of proteases
Frage 16
Frage
For Amantadine and Rimantadine is true:
Antworten
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resistance can develop rapidly
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they are effective against both type A and type B influenza
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they are effective against type A influenza viruses
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they interfere with the function of the viral M2 protein and block uncoating of the Virus particles
Frage 17
Frage
Mechanisms of action of drugs for treatment of HIV infection are:
Antworten
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inhibition of reverse transcriptase
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inhibition of HIV protease
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inhibition of HIV entry into the host cell
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inhibition of the insertion of proviral DNA. into the host cell genome
Frage 18
Frage
Point out the correct statements for Zidovudin;
Antworten
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it blocks HIV reverse transcriptase
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it blocks HIV protease
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it is a nucleoside analogue
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it can cause anemia and neutropenia
Frage 19
Frage
ADRS of Nucleoside and nucleotide reverse transcriptase inhibitors (NRTIs) are:
Antworten
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peripheral neuropathy
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pancreatitis
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polymyositis
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glaucoma
Frage 20
Frage
HIV protease inhibitors are:
Antworten
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Zidovudin
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Indinavir
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Ritonavir
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Aciclovir
Frage 21
Frage
For HIV protease inhibitors is true:
Antworten
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protease inhibition prevents maturation of the viral particles
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they are enzyme inducers
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they are enzyme inhibitors
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they are combined with other antiretroviral drugs in the treatment of HIV infection
Frage 22
Frage
ADRs of HIV protease inhibitors are:
Antworten
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hyperlipidaemia
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insulin resistance and hyperglycaemia
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hypoglycaemia
-
fat redistribution
Frage 23
Frage
Inhibitor of both hepatitis B virus (HBV) and HIV reverse transcriptases is:
Antworten
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Zidovudin
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Lamivudin
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Aciclovir
-
lndinavir
Frage 24
Frage
Protease inhibitor for treatment of chronic hepatitis C infection is:
Antworten
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Aciclovir
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Telaprevir
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Zidovudin
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Oseltamivir
Frage 25
Frage
Antimycobacterial drugs are:
Antworten
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Rifampicin
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Isoniazid
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Ethambutol
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Amoxicillin
Frage 26
Frage
Rifampicin (Rifampin):
Antworten
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is bactericidal antibiotic with antimycobacterial activity
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is antiviral drug
-
is broad spectrum antibiotic
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is enzyme inducer
Frage 27
Frage
Mechanism of action of Rifampicin (Rifampin) is
Antworten
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inhibition of cell wall synthesis
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inhibition of 50 S ribosomal subunit
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inhibition of DNA-dependent RNA polymerase
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increased cell membrane permeability
Frage 28
Frage
ADRs of Rifampicin (Rifampin) are:
Antworten
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heart failure
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orange-red color of urine and other secretions
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hepatotoxicity
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hypoglycaemia
Frage 29
Frage
Point out the correct statements for lsoniazid:
Antworten
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inhibits the synthesis of essential for mycobacteria mycolic acid
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it is metabolized by, acetylation
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it is specific for treatment of M. Tuberculosis
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it is active against broad spectrum of bacteria
Frage 30
Frage
ADRs of lsoniazld are:
Antworten
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renal impairment
-
peripheral neuropathy
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convulsions
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hepatitis
Frage 31
Frage
lsoniazid-induced peripheral neuropathy can be avoided by:
Antworten
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supplementation with vitamin B1
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supplementation with vitamin A
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supplementation with vitamin B6
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supplementation with vitamin B12
Frage 32
Frage
ADRs of Pyrazinamide are:
Antworten
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hepatotoxicity
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arrhythmia
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hyperuricaemia
-
hypoglycaemia
Frage 33
Frage
Ethambutol:
Antworten
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is bacteriostatic antimycobacterial drug
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may cause liver failure
-
may cause optic neuritis
-
inhibits synthesis of the mycobacterial cell wall
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