dermatology '23

Question 1

1.A 29-year-old man is bothered by a "cold sore" on his upper lip. After a week, he notices the appearance of several rounded, slightly erythematous lesions on the palms of his hands averaging 0.4 to 0.8 cm in size. Each of the lesions has a targetoid appearance with a central dark red area. After a course of acyclovir, the lesions on his hands disappear. Which of the following conditions did he most likely have:

Accepted Answer

Erythema multiforme

Answer

Molluscum contagiosum

Answer

Keratoacanthoma

Answer

Impetigo

Answer

Pemphigus vulgaris

Question 2

What do we give to treat generalised putular psoriasis?

Accepted Answer

Methotrexate

Answer

Cyclosporine

Answer

Topical corticosteroids

Answer

Retinoids

Question 3

1. A 17-year-old girl has the onset of "hives" over the past 3 hours. On physical examination there are irregular, slightly raised, erythematous patches from 1 to 6 cm in size over all surfaces of her body. The lesions are pruritic. The lesions gradually fade over the next day without therapy. Which of the following is the most likely diagnosis?

Accepted Answer

Prick test

Answer

Patch test

Answer

Tzanck test

Answer

Skin biopsy

Question 4

4. Three children with ages from 5 to 10 in a family are all affected by itching lesions on their hands for the past 2 weeks. On physical examination there are erythematous areas with superficial excoriation on the fingers and dorsa of the hands. These areas are linear to ovoid. Application of lindane-containing cream results in resolution of the lesions within a week. Infection with which of the following did these children most likely have?

Accepted Answer

Sarcoptes scabiei

Answer

Actinomyces israeli israeli

Answer

Candida albicans

Answer

Papovavirus

Answer

Trichophyton rubrum

Answer

Staphylococcus aureus

Question 5

5. A 9-year-old girl has developed a skin rash over the past 2 days. On physical examination there are vesicular lesions from 1 to 5 cm in diameter on her extremities and trunk. There are 2 lesions on her buccal mucosa. These lesions have a central red nodule surrounded by a zone of erythema. This child was given antibiotic therapy for a otitis media one week ago. What is the most likely diagnosis?

Accepted Answer

Stevens-Johnson syndrome

Answer

Dysplastic nevus syndrome

Answer

Icthyosis

Answer

Letterer-Siwe disease

Answer

Mycosis fungoides

Answer

Xeroderma pigmentosa

Question 6

8.Trauma to normal skin in psoriasis patients often results days later in new psoriatic lesions. This is a description of:

Accepted Answer

a. Köbner phenomenon

Answer

b. Gottron's sign

Answer

b. Auspitz sign

Answer

c. Candle sign

Answer

e. Groover sign

Question 7

9. Gottrons sign belongs to which disease;

Accepted Answer

Dermatomyositis

Answer

Morphea

Answer

DLE

Answer

SLE

Question 8

9.Over the past 4 months a 25-year-old woman has noted the appearance of a skin rash on her face when she spends more than an hour in the sun. On physical examination there is an erythematous malar skin rash. Laboratory studies show a positive antinuclear antibody (ANA) test with a titer of 1:256 and anti-double stranded DNA titer of 1:256. A punch biopsy of non- sun exposed skin is performed. Immunofluorescence staining on this normal skin reveals band- like deposition of IgG and C3 at the dermal-epidermal junction. Which of the following immunologic disorders is she most likely to have?

Accepted Answer

d) Systemic Lupus Erythematosus (SLE)

Answer

Polymyositsidermatomyosits

Answer

b) Discoid lupus erythematosus (DLE)

Answer

c) Systemic sclerosis (SS)

Answer

e) Graf versus host disease (GVHD)

Question 9

10.Match the first line treatment for early syphilis:

Accepted Answer

D. Benzathine penicillin

Answer

Doxycycline

Answer

B. Ceftriaxone

Answer

C. Benzylpenicillin

Answer

E. Crystalline penicillin

Question 10

10.Match the first line treatment for early Erisypelas:

Accepted Answer

C. Crystalline penicillin + clinda mycin

Answer

A. Crystalline penicilliin

Answer

B. Ceftriaxone

Answer

D. Benzathine penicillin

Question 11

11. Which of the following test is used in confirming early congenital syphilis:

Accepted Answer

d. FTA – ABS IgM

Answer

a. VDRL

Answer

b. FTA –ABS IgG

Answer

c. USR

Answer

e. TPHA

Question 12

12. Which of the following enzymes are used by HIV DNA —> RNA replication and for integration

Accepted Answer

b. RNA polymerase, integrase

Answer

a. RNA polymerase, reverse transcriptase

Answer

c. Integrase

Answer

d. Reverse transcriptase

Answer

e. Integrase, reverse transcriptase

Question 13

13. Not characteristic of morphea

Accepted Answer

c. Lung fibrosis

Answer

a. Hypopigmentation

Answer

b. Hyperpigmentation

Question 14

14. Which of the following it not used as an exfoliator

Accepted Answer

Click me as correct!!

Answer

Urea

Answer

Lactic acid

Answer

Salicylic acid

Answer

Retinoids

Answer

Eucerin

Question 15

15. Some long as bs about systemic generalised? psoriasis treatment

Accepted Answer

a. Biological treatment, Methotrexate, 3 others

Answer

b. IL-17 & IL- 23 blabla

Answer

c. TNF-alpha blabla

Question 16

16. Mach true statement about ecthyma:

Accepted Answer

c. Mixed streptococcal and staphylococcal infection

Answer

a. Infection caused by Candida

Answer

b. Staphylococcal infection

Answer

d. Symptom of deep fungal infection

Answer

e. Symptom of early syphilis

Question 17

17. 45 year-old male patient is manifesting homogenous erythematous patch on the chest that spreads peripherally from the centrally located small papule. There is a tendency to central clearing, the diameter of the whole lesion is 6 centimeters. According to the patient the lesion appeared around 4 weeks ago. There is no infiltration, no fever, no other complains. The patient does not recognize any causing factors, he works as a forester. Mark the most probable diagnosis:

Accepted Answer

d. Lyme borreliosis

Answer

a. Erysipelas

Answer

b. Urticaria

Answer

c. Polymorphic light eruption

Answer

e. Psoriasis

Question 18

18. The following are side effects of acitretin:

Accepted Answer

d. increased cholesteol

Answer

a. pancytopenia

Answer

b. hirsutism

Answer

c. immunosuppression

Answer

e. bone marrow suppression

Question 19

19. Intraepidermal blisters are the histological features of:

Accepted Answer

d. acantholysis

Answer

a. acanthosis

Answer

b. epidermotropism

Answer

c. lichenification

Answer

e. hyperkeratosis

Question 20

20. VDRL (-), FTA-ABS (+), TPHA (-): one can diagnose:

Accepted Answer

d. Latent early syphilis

Answer

a. Congenital syphilis

Answer

b. Latent late syphilis

Answer

c. Symptomatic late syphilis

Answer

e. Non-treponemal positive reaction

Question 21

21. During the treatment of acne with isotretinoin in 20-year old female patients:

Accepted Answer

e. contraception should be used for the entire treatment period and 2 months thereafter, blood levels of triglyceride and cholesterol should be checked

Answer

a. photoprotection is strongly recommended

Answer

b. tetracycline should be added to improve the efficiency of treatment

Answer

c. contraception should be used for the entire treatment period and 2 weeks thereafter, blood levels of aminotransferases should be checked

Answer

d. blood morphology has to be checked regularly

Question 22

22. Which of the following pigmented skin lesions is the most suspicious of being a melanoma:

Accepted Answer

e. Growing mole

Answer

a. Mole with uniform pigmentation

Answer

b. Elevated mole

Answer

c. Mole with diameter = 8 mm

Answer

d. Mole with irregular border

Question 23

23. In which case it is obligatory to order body CT scans and check the lymph-nodes

Accepted Answer

d. Melanoma clark V

Answer

a. Basal cell cancer

Answer

b. Keratoacanthoma

Answer

c. Melanoma clark I

Answer

e. Patch phase of mycosis fungoides

Question 24

24. Anticentromere antibodies (ACA) occur in patients with:

Accepted Answer

e. systemic scleroderma

Answer

a. dermatomyositis

Answer

b. antifosfolipidic syndrome

Answer

c. Sharp’s disease

Answer

d. periarteritis nodosa

Question 25

25. A 44 year old patient with by blisters on the skin and mucous membranes. The blisters rupture easily, leaving open sores. Microbiological tests revealed that there are no pathogenic bacterias on both affected and healthy skin. Blood tests revealed antibodies known as desmogleins. Which diagnosis is the most probable:

Accepted Answer

c. Pemphigus vulgaris

Answer

a. MCTD

Answer

b. Urticaria

Answer

d. Zoster

Answer

e. SLE

Question 26

26. Dyskeratosis it is:

Accepted Answer

d. keratinization of single cell within living layers of epidermis

Answer

a. feature of psoriasis

Answer

b. feature of lichen planus

Answer

c. Balloon degeneration of keratinocytes

Answer

e. otherwise the Koebner symptom

Question 27

27. Which sentence is true:

Accepted Answer

b. Majority of skin lymphomas are T-cell lymphomas

Answer

a. Majority of skin lymphomas are B-cell lymphomas

Answer

c. Skin t-cell lymphomas affects young individuals mainly

Answer

d. Mycosis fungoides is always treated with chemotherapy

Answer

e. Lentigo-malignant melanoma is one of the most aggressive types of melanoma

Question 28

28. Which of the following human leukocyte antigens is most often associated with type I psoriasis:

Accepted Answer

e. HLA-Cw6

Answer

a. HLA-Cw2

Answer

b. HLA-B13

Answer

c. HLA-B27

Answer

d. HLA-B57

Question 29

29. Main criterias of systemic lupus erythematosus do not include:

Accepted Answer

e. Lower levels of C3 i C4 complement in the blood

Answer

a. leukopenia

Answer

b. Sm antibodies

Answer

c. Pericarditis

Answer

d. UV intolerance

Question 30

30. Match false statement describing antinuclear antibodies (ANA):

Accepted Answer

e. Occur in all patients with discoid lupus erythematosus

Answer

a. They can be induced by some drugs

Answer

b. They can be transmitted through placenta

Answer

c. Their occurrence can be affected by other diseases like infections

Answer

d. They are detected by indirect immunofluorescence

Question 31

31. Match true correlation(s) between connective tissue diseases and types of antinuclear antibodies:

Accepted Answer

a. dermatomiositis - Mi-2 antibodies / SCLE - La (SS-B) antibodies

Answer

b. systemic lupus erythematosus - anticentromere antibodies

Answer

c. Pemphigus- MI2 antibodie, Pemphigoid- desmoglein antibodies

Answer

d. Sclerodermia- ds DNA antibodies, ssDNA antibodies

Answer

e. systemic scleroderma - Ro (SS-A) antibodies

Question 32

32. A 77 year old male patient with nodular tumor with pearly border, dilated blood vessels and a central ulceration, present on the scalp for 9 months. The most probable diagnosis:

Accepted Answer

c. Basal cell cancer

Answer

a. Squamous cell cancer

Answer

b. Malignant in situ melanoma

Answer

d. Actinic keratosis

Answer

e. Tuberculosis

Question 33

33. Which of the following are malignant disorders suspected to be metastatic disease:

Accepted Answer

d. Tumoral phase of mycosis fungoides and melanoma Clark IV

Answer

a. Cutaneous horn and Duhring disease

Answer

b. Melanoma Clark V and patch phase of mycosis fungoides

Answer

c. Basal cell cancer and infiltrative phase of mycosis fungoides

Answer

e. Sezary syndrome and Stevens-Johnson syndrome

Question 34

35. IgA antibodies against tissue transglutaminase are the hallmark of:

Accepted Answer

a. Dermatitis herpetiformis

Answer

b. Morphea

Answer

c. Pemphigoid

Answer

d. SLE

Answer

e. Hashimoto thyroiditis

Question 35

36. Sezary syndrome:

Accepted Answer

a. Requires chemotherapy

Answer

b. Is characterized by presence of ssDNA antibodies in the blood

Answer

c. Is the B-cell lymphoma

Answer

d. Can be treated by PUVA-therapy

Answer

e. Can be diagnosed when erythrodermia and enlargement of lymph-nodes are found

Question 36

37. Mark the target antigen(s) for autoimmunological reactions in pemphigus vulgaris:

Accepted Answer

a. Desmoglein 3

Answer

b. Desmoglein 1

Answer

c. Collagen XVII

Answer

d. Laminin 6

Answer

e. Desmoglein 1 and 3

Question 37

38. Erythrasma is a/an:

Accepted Answer

a. erythematic lesions in body folds caused by Corynebacterium minutissimum

Answer

b. skin changes due to seborrheic dermatitis

Answer

c. skin lesions in the first stage of boreliosis

Answer

d. skin lesions of the trunk caused by Malassezia

Answer

e. infection of the scalp caused by Malassezia

Question 38

39. Immunological disorders, diabetes mellitus, pregnancy, chronic steroid and antibiotic therapy, wearing dentures are main the risk factors of:

Accepted Answer

a. Oral candidiasis

Answer

b. Pemphigus vulgaris

Answer

c. Cranial herpes zoster

Answer

d. Leukoplakia

Answer

e. Mucosal lichen planus

Question 39

40. Mark the most common trigger in pediatric acute urticaria:

Accepted Answer

d. Viral and bacterial infections

Answer

a. Physical exercises

Answer

b. Low temperature

Answer

c. UV irradiation

Answer

e. High temperature

Question 40

41. The 58-year old female patient manifests the erythematous skin lesion on left leg, which has a sharply demarcated raised edge. It appears as a red, swollen, warm, hardened and painful. There is a high fever, symptoms and lesion on the leg appeared a week ago. One can diagnose:

Accepted Answer

d. Erysipelas

Answer

a. Lyme boreliosis

Answer

b. Lichen planus

Answer

c. Mycosis fungoides

Answer

e. Psoriasis

Question 41

42. What is the “window period”. Choose the correct answer:

Accepted Answer

c. Period between HIV infection and the beginning of antibody production

Answer

a. Unprotected sex with a person during the window period is 100% safe

Answer

b. During this period the infected patient always has positive HIV antibodies

Answer

d. May last up to 2 years

Answer

e. Period between HIV infection and the beginning of AIDS symptoms

Question 42

43. Urticaria with a sudden onset and symptoms lasting less than 6 weeks is a definition:

Accepted Answer

c. Acute urticaria

Answer

a. Chronic urticaria

Answer

b. Allergic urticaria

Answer

d. Non-allergic urticaria

Answer

e. Physical urticaria

Question 43

44. Seronegative period in primary syphilis lasts from 3 weeks till:

Accepted Answer

6 weeks

Answer

7 weeks

Answer

8 weeks

Answer

9 weeks

Answer

5 weeks

Question 44

45. The primary lesion in psoriasis is a:

Accepted Answer

c. Papule

Answer

a. Pustula

Answer

b. Macula

Answer

d. Patch

Answer

e. Scale

Question 45

46. Nontreponemal serological tests are:

Accepted Answer

c. USR, VDRL, RPR

Answer

a. VDRL, TPHA, FTA

Answer

b. FTA-ABS, TPHA, RPR

Answer

d. VDRL, FTA, USR

Answer

e. USR, TPHA, VDRL

Question 46

47. What is not the risk factor for melanoma:

Accepted Answer

d. Skin type V according to Fitzpatrick

Answer

a. Sunburns

Answer

b. Large numbers of benign moles

Answer

c. Atypical mole

Answer

e. Skin type I according to Fitzpatrick

Question 47

48. Macerated, inflammatory lesions with satellite papules localized under the breast in obese women are probably the symptoms of:

Accepted Answer

b. Candidiasis

Answer

a. Seborrheic dermatitis

Answer

c. Bacterial infection

Answer

d. Dermatophyte infection

Answer

e. Contact dermatitis

Question 48

49. A 6-year old male patient diagnosed with atopic dermatitis manifests additional skin lesions - erosions covered by golden - yellow crusts located on all the face area. One might diagnose:

Accepted Answer

e. impetiginization

Answer

a. contact dermatitis

Answer

b. contagious impetigo

Answer

c. exacerbation of atopic dermatitis

Answer

d. lichenification

Question 49

50. Which mole should immediately be surgically removed:

Accepted Answer

e. Diameter greater than 6 mm, changing colour, asymetric shape

Answer

a. Diameter greater than 6 mm, uniform pigmentation and borders, elevated surface

Answer

b. Localized on the acral parts of the body

Answer

c. mole with hairs , elevated surface

Answer

d. Diameter smaller than 6 mm, regular border

Question 50

51. A 40-year-old male presents to clinic with a rash on the scalp, extensor elbows, knees and umbilicus. You note sharply demarcated erythematous plaques with silvery scale in those locations; there is no central clearing, no itching. The soles of the feet are normal. What is the most likely diagnosis?

Accepted Answer

b. Psoriasis

Answer

a. Allergic contact dermatitis

Answer

c. Seborrheic dermatitis

Answer

d. Secondary syphilis

Answer

e. Atopic dermatitis

Answer

f. bullous pemphigoid

Answer

g. pemphigus

Question 51

52. Mark the laboratory findings not characteristic for SLE :

Accepted Answer

b. Acantholysis

Answer

a. High levels of dsDNA antibodies

Answer

c. Positive photo-tests (indicating increased photosensitivity)

Answer

d. Pancytopeny (decreased levels of RBC, WBC, Platelets)

Answer

e. Proteinuria >0.5 g daily

Question 52

53. Which of the following is not an IgE mediated allergic reaction:

Accepted Answer

e. Contact dermatitis

Answer

a. Atopic dermatitis

Answer

b. Rhinitis

Answer

c. Systemic anaphylaxis

Answer

d. Acute urticaria

Question 53

54. Choose the example of zoophilic infection:

Accepted Answer

a. Microsporum scalp infection

Answer

b. Chickenpox

Answer

c. Herpes zoster

Answer

d. Pityriasis versicolor

Answer

e. Erysipelas

Question 54

55. Mark true sentence:

Accepted Answer

d. Contact dermatitis is an example of type IV of immunological reaction

Answer

a. Urticaria is an example of type IV of immunological reaction

Answer

b. In majority of cases with atopic dermatitis IgE levels are normal

Answer

c. Nickel sulfate is a rare cause of contact dermatitis

Answer

e. Antihistaminic drugs are used in each case of contact dermatitis

Question 55

56. Which sentence is true:

Accepted Answer

c. squamous cell cancer usually affects lower lip

Answer

a. squamous-cell cancer is characterized by pearly border and teleangiectasia on the surface

Answer

b. leucoplakia can be easily removed during examination

Answer

d. Basal-cell cancer affects usually middle-age individuals

Answer

e. the risk for squamous cell cancer is 90% when actinic keratosis is found

Question 56

57. Which sentence is true:

Accepted Answer

C. Majority of skin lymphomas are T-cell lymphomas

Answer

A. Majority of skin lymphomas are B-cell lymphomas

Answer

B. Mycosis fungoides is always treated with chemotherapy

Answer

D. Skin t-cell lymphomas affects young individuals mainly

Answer

E. Mycosis fungoides is always treated with anti-fungal

Question 57

58. A 77-year old male patient manifests disease as general erythroderma, lymphadenopathy, hepatomegaly, intense itching. The symptoms are present for few months. According to the patient's history disease he has been affected with contact dermatitis for many years. You can diagnose the most probable skin disorder:

Accepted Answer

a. Sezary syndrome

Answer

b. Generalized scleroderma

Answer

c. Lichen planus

Answer

d. Psoriasis

Answer

e. Pemphigus

Question 58

59. Which of the following melanoma types is the most frequent:

Accepted Answer

c. Superficial-spreading

Answer

a. Nodular

Answer

b. Mucosal

Answer

d. Amelanocytic

Answer

e. Acral

Question 59

60. The first line of treatment of erysipelas is/are:

Accepted Answer

c. Crystalline penicillin + clindamycin

Answer

a. Crystalline penicillin

Answer

b. Erythromycin

Answer

d. Ceftriaxone + clindamycin

Answer

e. Hydrocortisone

Question 60

There was a question like - if the mother has anti La SS-b antibodies what is it likely for her infant to have?

Accepted Answer

NLE

Answer

don't know what else was asked

dermatology '23

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