Management of diabetes

Beschreibung

RACP Endocrinology (Management of Diabetes) Quiz am Management of diabetes , erstellt von Jeku Jacob am 26/04/2016.
Jeku Jacob
Quiz von Jeku Jacob, aktualisiert more than 1 year ago
Jeku Jacob
Erstellt von Jeku Jacob vor etwa 8 Jahre
38
3

Zusammenfassung der Ressource

Frage 1

Frage
Which of the following mechanisms best describes the mode of action of the sulphonylurea class of drugs?
Antworten
  • Stimulates insulin synthesis.
  • Enhances insulin binding to the beta cell insulin receptor.
  • Stimulates insulin secretion.
  • Stimulates conversion of proinsulin to insulin and C-peptide.
  • Stimulates beta cell proliferation.

Frage 2

Frage
The deterioration in glycaemic control over time seen in patients with type 2 (non-insulin-dependent) diabetes mellitus is primarily due to:
Antworten
  • medication non-compliance.
  • increasing insulin resistance.
  • increasing obesity.
  • decreasing insulin secretion.
  • reduced energy expenditure

Frage 3

Frage
Which of the following drugs used in diabetes treatment is most likely to cause hypoglycemia?
Antworten
  • Repaglinide.
  • Metformin.
  • Acarbose.
  • Rosiglitazone.
  • Orlistat.

Frage 4

Frage
In a patient with Type 2 diabetes which of the following co-existing clinical situations is the strongest contraindication to the use of a thiazolidinedione drug?
Antworten
  • Fatty liver disease.
  • Peripheral vascular disease.
  • Severe congestive cardiac failure.
  • Proliferative diabetic retinopathy.
  • Serum creatinine 200μmol/L.

Frage 5

Frage
In patients with Type 1 Diabetes, the greatest benefit in using a long acting insulin analogue is in reducing which of the following
Antworten
  • Diabetic Retinopathy
  • Nocturnal hypoglycemia
  • insulin hypersensitivity
  • preprandial hyperglycemia
  • microalbuminuria

Frage 6

Frage
Glucagon-like peptide–1, secreted postprandially by the L-cells in the intestine, increases which of the following?
Antworten
  • Gastric emptying.
  • Body weight.
  • Insulin secretion.
  • Hepatic glucose output.
  • Insulin sensitivity (sulphonylurea, thiazolidinediones)
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